Evidence map›Paper›PMID 41786707›Full record

ArticleNature communications2026

Swapped and non-swapped TRAAK states co-exist in membranes at a ratio influenced by temperature.

Yue Ma, Katrin Ackermann, Qaiser Waheed, Vincent Postis, Terry K Smith, Bela E Bode, Christos Pliotas

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue MaBioEmPiRe Centre for Structural Biological EPR Spectroscopy, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0001-5934-0497
Katrin AckermannEaStCHEM School of Chemistry, Biomedical Sciences Research Complex and Centre of Magnetic Resonance, University of St Andrews, St Andrews, UK.
Qaiser WaheedBioEmPiRe Centre for Structural Biological EPR Spectroscopy, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-7566-2506
Vincent PostisWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.
Terry K SmithSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, UK.ORCID http://orcid.org/0000-0003-1994-2009
Bela E BodeEaStCHEM School of Chemistry, Biomedical Sciences Research Complex and Centre of Magnetic Resonance, University of St Andrews, St Andrews, UK.ORCID http://orcid.org/0000-0002-3384-271X
Christos PliotasBioEmPiRe Centre for Structural Biological EPR Spectroscopy, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. christos.pliotas@manchester.ac.uk.ORCID http://orcid.org/0000-0002-4309-4858

Funding

RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S018069/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/W019795/1
6 · The paper itself

Abstract

The potassium two-pore domain (K2P) ion channel TRAAK is expressed in the nervous system and regulates the fast action potential in membranes. Like all K2P channels, TRAAK possesses a distinct extracellular cap, which adopts a swapped and a non-swapped conformation

Indexed as

Cell MembranePotassium Channels, Tandem Pore DomainAnimalsElectron Spin Resonance SpectroscopyProtein ConformationProtein DomainsTemperaturePotassium Channels, Tandem Pore Domain

Identifiers

PMID41786707
PMCPMC13087257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.