Evidence map›Paper›PMID 41786675›Full record

ArticleThe Laryngoscope2026

Transoral Minimal Access Mandibular Reconstruction Using Fibula Free Flap in Osteoradionecrosis.

Derek J Vos, Emily Zhang, Neil N Patel, Sara W Liu, Peter J Ciolek, Brandon L Prendes, Eric D Lamarre, Michael A Fritz

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Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Derek J VosCase Western Reserve University, Cleveland, Ohio, USA.
Emily ZhangCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.
Neil N PatelCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.ORCID 0000-0003-1365-9130
Sara W LiuCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.
Peter J CiolekCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.
Brandon L PrendesCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.
Eric D LamarreCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.
Michael A FritzCleveland Clinic Head and Neck Institute, Cleveland, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the use, indications, and outcomes of a limited transoral approach for segmental mandibulectomy reconstruction with minimal access vessel isolation and anastomoses in patients with mandibular osteoradionecrosis.

methodsRetrospective review of patients who have undergone FFF reconstruction of segmental mandibulectomy via transoral plating and inset at our institution from 2022 to 2024.

resultsNine patients (median age of 66, 100% male) with mandibular ORN underwent FFF reconstruction via transoral approach with minimal access vessels isolation. The majority of patients failed conservative management of ORN, with eight patients receiving prior antibiotic therapy and seven undergoing hyperbaric oxygen therapy. Preoperative fracture/nonunion and fistula were noted in seven and four patients, respectively. The median length of hospitalization following this procedure was 6 days (range: 4-9). One patient developed nonunion in the postoperative period and required revision with anterolateral thigh fascia lata free flap and iliac crest bone grafting. An additional patient required takeback for hematoma and successful vascular salvage; however, complications were otherwise minimal, with no other patients experiencing operating room takeback, readmission within 30 days, hematoma, fistulas, or flap compromise. All patients demonstrated clinical and radiographic arrest of ORN at most recent follow-up. Median follow-up length was 13.9 months (range 7.7-34).

conclusionMandibular reconstruction using a transoral approach with FFF provides a promising alternative to the traditional transcervical approach for patients with osteoradionecrosis, potentially reducing morbidity and improving outcomes. LEVEL OF EVIDENCE: 4:

Indexed as

FibulaFree Tissue FlapsMandibular DiseasesMandibular ReconstructionOsteoradionecrosisAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomefibula free flapmandibular osteoradionecrosisminimal access

Identifiers

PMID41786675
PMCPMC13158837

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