Evidence map›Paper›PMID 41786620›Full record

Trial reportPhysical therapy2026

Effects of home-based cardiac rehabilitation integrated in the cardiac care bridge transitional care program on the physical functioning of older patients who are frail: secondary analysis of a randomized trial.

Michel S Terbraak, Lotte Verweij, Patricia Jepma, Marike van der Schaaf, Harald T Jørstad, Ron J G Peters, Bianca M Buurman, Wilma J M Scholte Op Reimer

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michel S TerbraakLocation Academic Medical Center, Department of Cardiology, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, Noord Holland, the Netherlands.ORCID 0000-0002-0265-4556
Lotte VerweijInstitute for Implementation Science in Health Care, Department of clinical nursing, University of Zurich, Universitätstrasse 84, Zurich 8006, Zurich, Switzerland.ORCID 0000-0002-4727-0126
Patricia JepmaLocation VU University Medical Center, Department of Medicine for Older People, Amsterdam UMC, de Boelelaan, Amsterdam 1109, Noord Holland, the Netherlands.ORCID 0000-0003-1271-6869
Marike van der SchaafCenter of Expertise Urban Vitality, Faculty Health, Amsterdam University of Applied Sciences, Amsterdam 1097 DZ, Noord Holland, the Netherlands.ORCID 0000-0001-7272-4698
Harald T JørstadLocation Academic Medical Center, Department of Cardiology, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, Noord Holland, the Netherlands.ORCID 0000-0003-3617-3256
Ron J G PetersLocation Academic Medical Center, Department of Cardiology, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, Noord Holland, the Netherlands.ORCID 0000-0002-3642-5022
Bianca M BuurmanLocation VU University Medical Center, Department of Medicine for Older People, Amsterdam UMC, de Boelelaan, Amsterdam 1109, Noord Holland, the Netherlands.ORCID 0000-0001-7139-6178
Wilma J M Scholte Op ReimerLocation Academic Medical Center, Department of Cardiology, Amsterdam UMC, Meibergdreef 9, 1105AZ, Amsterdam, Noord Holland, the Netherlands.ORCID 0000-0002-2079-961X

Funding

Dutch Research Council 023.009.036Netherlands Organization for Health Research and Development (ZonMw) 520002002
6 · The paper itself

Abstract

importanceOlder patients hospitalized for cardiovascular disease (CVD) are at risk of physical function decline and adverse health outcomes. Cardiac rehabilitation (CR) improves physical functioning but is underutilized by older patients. Home-based CR potentially improves utilization, yet its effectiveness in older patients who are frail remains understudied.

objectiveThe objective of this study was to investigate the effects of a transitional-care integrated home-based CR program on physical functioning in older patients who are frail after CVD hospitalization.

designThis was a prespecified secondary analysis of physical functioning at the 6-month follow-up in the cardiac care bridge multicenter randomized trial.

settingA home-based setting was used.

participantsThe study participants were patients who were frail and ≥70 years old after CVD hospitalization.

interventionThe intervention was transitional care followed by physical therapist led home-based CR and community nurse visits. MAIN OUTCOMES AND MEASURES: The primary physical function outcome was the Short Physical Performance Battery (SPPB) in cases with complete follow-up data. Secondary outcomes included the 2-min step test, grip strength, and Amsterdam Linear Disability Scale. Sensitivity analyses included an intention-to-treat analysis by multiple imputation of the full cohort.

resultsIn total, 85 of 153 participants in the intervention group and 85 of 153 participants in the control group were analyzed (mean age = 82.6 [SD = 6.3] years; 46% men; median of 2 [interquartile range = 1-4] comorbidities). At the 6-month follow-up, more participants in the intervention group than in the control group demonstrated SPPB improvement (61% vs 51%) or maintenance (29% vs 12%), and fewer deteriorated (11% vs 37%). The mean SPPB values at 6 months were 6.3 (SD = 0.3) and 5.5 (SD = 0.2), respectively, with a mean difference of 0.8 (95% CI = 0.0-1.6), favoring the intervention group. No between-group differences were observed in the 2-min step test, grip strength, or Amsterdam Linear Disability Scale.

conclusionsAmong older patients who were frail and had CVD, a comprehensive transitional-care program with integrated home-based CR resulted in clinically relevant improvements in physical functioning. RELEVANCE: The results substantiate the effectiveness of home-based CR in older patients who are frail and have CVD.

Indexed as

Cardiac RehabilitationCardiovascular DiseasesFrail ElderlyHome Care ServicesPhysical Functional PerformanceTransitional CareAgedAged, 80 and overFemaleHumansMalecardiac rehabilitationfrailhome-basedolderpatientsphysical

Identifiers

PMID41786620
PMCPMC13064644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.