Evidence map›Paper›PMID 41786500›Full record

ArticleThe European respiratory journal2026

High prevalence of TSC2 mutations in lung tissue samples from patients with sporadic lymphangioleiomyomatosis.

Elias Bou Farhat, Victoria-Elisabeth Gruber, Katarzyna Klonowska, Zachary T Herbert, Suzanne Miller, Renata Langfort, Yoichiro Mitsuishi, Simon R Johnson, Elzbieta Radzikowska, Kuniaki Seyama and 4 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The European respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elias Bou FarhatDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Victoria-Elisabeth GruberDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Katarzyna KlonowskaDepartment of Cancer Genetics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.ORCID https://orcid.org/0000-0001-9494-8801
Zachary T HerbertMolecular Biology Core Facilities, Dana-Farber Cancer Institute, Boston, MA, USA.
Suzanne MillerCentre for Respiratory Research, University of Nottingham, NIHR Biomedical Research Centre, Nottingham, Biodiscovery Institute and National Centre for LAM, Nottingham, UK.ORCID https://orcid.org/0000-0001-8508-1871
Renata LangfortDepartment of Pathology, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.
Yoichiro MitsuishiDepartment of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Simon R JohnsonCentre for Respiratory Research, University of Nottingham, NIHR Biomedical Research Centre, Nottingham, Biodiscovery Institute and National Centre for LAM, Nottingham, UK.ORCID https://orcid.org/0000-0002-9837-2763
Elzbieta RadzikowskaDepartment of Lung Diseases and Oncology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.ORCID https://orcid.org/0000-0002-2585-8594
Kuniaki SeyamaDepartment of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Elizabeth P HenskeDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Joel MossCritical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jason L HornickDepartment of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
David J KwiatkowskiDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA dk@rics.bwh.harvard.edu.

Funding

Tuberous Sclerosis-Pathway and PathogenesisP01CA120964 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI David J. Kwiatkowski · 2007 to 2026
$35.9M
NCI NIH HHS P01 CA120964
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41786500
PMCPMC13283343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.