Evidence map›Paper›PMID 41786079›Full record

ArticleJournal of vascular surgery. Venous and lymphatic disorders2026

Combined treatment of deep and superficial venous reflux accelerates ulcer healing and improves symptoms: A real-world retrospective study.

Wei Zheng, Zongheng Gu, Hui Zhao, Changbao Yan, Jie Zhang, Liang Zhao, Yingfeng Wu

Abstract readComparative Study
In one paragraph

Article in Journal of vascular surgery. Venous and lymphatic disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei ZhengDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China; Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, PR China.
Zongheng GuDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China.
Hui ZhaoDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China.
Changbao YanDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China.
Jie ZhangDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China.
Liang ZhaoDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China.
Yingfeng WuDepartment of Vascular Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, PR China; Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, PR China. Electronic address: wyfxgwk@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal surgical strategy for treating chronic venous disease with concomitant deep and superficial reflux but without iliac/proximal obstruction remains unclear. This study aimed to compare clinical symptoms, health-related quality-of-life, and ulcer outcomes between superficial venous surgery alone and combined deep-superficial surgery (performed concurrently or in stages).

methodsIn this single-center retrospective cohort, 229 patients were grouped by treatment and received superficial-only (n = 138), concurrent deep + superficial (n = 49), or staged deep + superficial (n = 42) interventions. Outcomes were Venous Clinical Severity Score (VCSS), Chronic Venous Insufficiency Questionnaire-20 (CIVIQ-20) at baseline and follow-up (1, 3, and 6 months, and last follow-up), ulcer outcomes (n = 59) assessed by healing rates and Kaplan-Meier time-to-healing analysis, duplex valve competence after deep intervention, and complications. Analyses used Welch one-way analysis of variance with Games-Howell post hoc and log-rank testing.

resultsBaseline characteristics were comparable (baseline VCSS 8.6±3.3, 9.6±4.0, and 9.0±3.9; P = .32). Between-group differences in VCSS were significant at 1 month (P = .012), 6 months (P < .001), and last follow-up (P = .017). Staged treatment reduced VCSS vs superficial-only at 1 month (mean difference [MD], -1.47; P

conclusionsIn patients with chronic venous disease with concomitant deep and superficial reflux but no iliac obstruction, adding deep reflux correction (concurrent or staged) was associated with greater and more durable symptom relief and better quality of life than superficial-only surgery, with high duplex-confirmed competence and low complication rates; ulcer healing time may be accelerated.

Indexed as

Varicose UlcerVascular Surgical ProceduresVenous InsufficiencyWound HealingAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedQuality of LifeRetrospective StudiesSeverity of Illness IndexTime FactorsTreatment OutcomeChronic venous diseaseDeep venous refluxSuperficial venous refluxVenous ulcer

Identifiers

PMID41786079
PMCPMC13054411

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.