Evidence map›Paper›PMID 41785438›Full record

ArticleJCO precision oncology2026

Impact of Germline

Lingaku Lee, Yuichi Tachibana, Susumu Matsuo, Yusuke Niina, Takashi Fujiyama, Terumasa Hisano, Rie Sugimoto, Tetsuro Akashi, Keiichiro Ogoshi, Masayuki Furukawa

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in JCO precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lingaku LeeDepartment of Hepato-Biliary-Pancreatology, NHO Kyushu Cancer Center, Fukuoka, Japan.ORCID 0000-0003-1005-5606
Yuichi TachibanaDepartment of Hepato-Biliary-Pancreatic Medicine, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
Susumu MatsuoDepartment of Gastroenterology, NHO Fukuoka Higashi Medical Center, Fukuoka, Japan.
Yusuke NiinaDepartment of Hepato-Biliary-Pancreatology, NHO Kyushu Cancer Center, Fukuoka, Japan.
Takashi FujiyamaDepartment of Gastroenterology, NHO Fukuoka Higashi Medical Center, Fukuoka, Japan.ORCID 0000-0003-0496-7684
Terumasa HisanoDepartment of Hepato-Biliary-Pancreatology, NHO Kyushu Cancer Center, Fukuoka, Japan.ORCID 0000-0002-4965-086X
Rie SugimotoDepartment of Hepato-Biliary-Pancreatology, NHO Kyushu Cancer Center, Fukuoka, Japan.ORCID 0000-0003-3906-9307
Tetsuro AkashiDepartment of Hepato-Biliary-Pancreatic Medicine, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.ORCID 0000-0002-3788-6787
Keiichiro OgoshiDepartment of Gastroenterology, NHO Fukuoka Higashi Medical Center, Fukuoka, Japan.
Masayuki FurukawaDepartment of Hepato-Biliary-Pancreatology, NHO Kyushu Cancer Center, Fukuoka, Japan.ORCID 0000-0002-1278-0775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGermline

methodsThis multicenter retrospective study was performed in 178 patients with histologically confirmed APC who received mFFX, comprising 17 g

resultsMedian PFS was significantly longer in g

conclusiong

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBRCA2 ProteinGerm-Line MutationPancreatic NeoplasmsAdultAgedAged, 80 and overFemaleFluorouracilHumansIrinotecanLeucovorinMaleMiddle AgedOxaliplatinRetrospective StudiesBRCA2 ProteinFluorouracilfolfirinoxIrinotecanLeucovorinOxaliplatin

Identifiers

PMID41785438
PMCPMC12991332

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.