Evidence map›Paper›PMID 41785202›Full record

ArticlePLOS global public health2026

"Miss, I want itchy medicine": Understanding what, why, and how antibiotics are used in Central Java province, Indonesia through the drug bag method.

Soe Yu Naing, Mira L Schneiders, Dhini Ningrum, Tri Nurdianti, Juliëtte Severin, Koen Peeters Grietens, Jaap A Wagenaar, Anis Karuniawati

Erratum issuedAbstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Soe Yu NaingDivision of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-3785-7633
Mira L SchneidersDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-4149-3484
Dhini NingrumDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Tri NurdiantiDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Juliëtte SeverinDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-5222-3017
Koen Peeters GrietensDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.ORCID https://orcid.org/0000-0001-6570-9887
Jaap A WagenaarDivision of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Anis KaruniawatiDepartment of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic use is shaped by access, knowledge, norms, and practices, yet remains poorly understood in many community settings worldwide. To address these gaps, we investigated community antibiotic use in six villages across Sukoharjo, Karanganyar, and Klaten districts of Central Java province in Indonesia. This study focused on three key questions: (i) which antibiotics are accessible in community settings; (ii) how do community members recognize and understand these antibiotics; and (iii) what social, economic, cultural, and contextual factors drive antibiotic use. Between April and May 2024, 36 drug bag interviews, in which locally available antibiotics were purchased, compiled, and used in household pile-sorting activities, were conducted with community members. Complementary ethnographic fieldwork included simulated patient visits, informal conversations, and participant observations in community settings and at local pharmacies and shops (Warungs). This study found that knowledge of antibiotics and Indonesian medicine labels was generally low, while access to antibiotics without prescription, particularly from pharmacies and Warungs, was high. Access antibiotics, such as amoxicillin and tetracycline, were the most commonly used and recognized, while Watch antibiotics, including aminoglycosides, were also popular for self-medication, especially in topical forms. Common reasons for self-medication included convenience, ease of access, and lower cost. Practices such as stopping treatment early, repurposing antibiotics, and sharing them among family members were commonly adopted. This study identified multiple intersecting factors influencing antibiotic use in community settings. The findings highlight that effective antibiotic stewardship requires not only policies to restrict non-prescription sales but also interventions that address the social, economic, and cultural drivers of self-medication.

Identifiers

PMID41785202
PMCPMC12962538

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.