Evidence map›Paper›PMID 41784874›Full record

ArticleInternational journal of clinical oncology2026

Comprehensive assessment of postoperative quality of life and risk factors after robot-assisted radical prostatectomy using the EPIC questionnaire.

Toru Sakatani, Kimihiko Masui, Toshihiro Magaribuchi, Akihiro Hamada, Kei Mizuno, Takayuki Sumiyoshi, Yuki Kita, Takashi Kobayashi, Takayuki Goto

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Article in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Toru SakataniDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Kimihiko MasuiDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Toshihiro MagaribuchiDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Akihiro HamadaDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Kei MizunoDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takayuki SumiyoshiDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yuki KitaDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takashi KobayashiDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. selecao@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0003-1069-2816
Takayuki GotoDepartment of Urology, Kyoto University School of Medicine, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRobot-assisted radical prostatectomy (RARP) is a standard treatment for localized prostate cancer. This procedure provides favorable oncologic outcomes but poses functional challenges, particularly urinary incontinence and sexual dysfunction, that can affect patients' quality of life (QOL). This study examined predictive factors for postoperative recovery of urinary, sexual, and bowel functions using the Expanded Prostate Cancer Index Composite (EPIC) questionnaire.

methodsThis single-center retrospective study included 279 patients who underwent RARP between 2011 and 2023. Health-related QOL was assessed preoperatively and up to 18 months postoperatively using the EPIC questionnaire. Recovery was defined as achieving ≥90% of baseline scores at 18 months. Firth's penalized logistic regression and baseline-adjusted analyses were performed to identify factors associated with poor recovery.

resultsUrinary function improved gradually, but 39.8% of patients showed suboptimal recovery at 18 months. In multivariable Firth's penalized logistic regression analysis, longer console time was independently associated with poor urinary incontinence recovery (OR 2.15, 95% CI 1.14-4.17). Ratio-based analyses suggested age-related differences in sexual recovery; however, baseline-adjusted analyses demonstrated a dissociation between postoperative sexual function and sexual bother. Nerve-sparing status was not independently associated with urinary and sexual recovery. Bowel function remained stable.

conclusionLonger console time was independently associated with poorer recovery of urinary continence after RARP, likely reflecting surgical complexity rather than a direct causal effect. Baseline-adjusted analyses revealed a dissociation between postoperative sexual function and sexual bother, underscoring the limitations of function-based QOL assessment and the need for patient-centered counseling and shared decision-making in RARP.

Indexed as

ProstatectomyProstatic NeoplasmsQuality of LifeRobotic Surgical ProceduresAgedHumansMaleMiddle AgedPostoperative ComplicationsPostoperative PeriodRetrospective StudiesRisk FactorsSurveys and QuestionnairesUrinary IncontinenceEPIC QuestionnaireProstate cancerRobotic assisted radical prostatectomySexual functionUrinary incontinence

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.