Evidence map›Paper›PMID 41783718›Full record

ArticleCase reports in ophthalmology

Evaluation of Reticular Pseudodrusen by Polarization-Sensitive Optical Coherence Tomography: Case Report.

Ryo Terao, Chihiro Tsusu, Yuki Saeki, Kazuki Yashiro, Mami Ota, Shuichiro Aoki, Kohdai Kitamoto, Keiko Azuma

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryo TeraoDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Chihiro TsusuDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Yuki SaekiDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Kazuki YashiroDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Mami OtaDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Shuichiro AokiDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Kohdai KitamotoDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Keiko AzumaDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Reticular pseudodrusen (RPD) are an important clinical biomarker associated with progression to late age-related macular degeneration (AMD). We report polarization-sensitive optical coherence tomography (PS-OCT) findings in a case of RPD and evaluate the entropy characteristics of these lesions. Case Presentation: A 73-year-old man presented for evaluation of retinal angiomatous proliferation in his right eye. The left eye demonstrated multiple round, white-yellowish macular lesions consistent with RPD. Optical coherence tomography (OCT) angiography showed no macular neovascularization in the left eye. Swept-source (SS-OCT) revealed hyperreflective, spike-like deposits between the photoreceptor outer segments (PROSs) and the retinal pigment epithelium. Corresponding PS-OCT B-scans demonstrated moderately elevated polarimetric entropy values at the same locations. Conclusion: PS-OCT successfully visualized RPD as moderately high-entropy lesions in the PROS layer, suggesting that these deposits are composed of non-retinal pigment epithelium material, such as lipids or inflammatory cells. These findings indicate that PS-OCT may serve as a useful complementary modality for detecting RPD and may enhance current imaging strategies for assessing RPD and monitoring AMD progression.

Indexed as

Age-related macular degenerationPolarization sensitive optical coherence tomographyReticular peudodrusenRetinal pigment epitheliumSubretinal drusenoid deposits

Identifiers

PMID41783718
PMCPMC12956322

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