Evidence map›Paper›PMID 41783697›Full record

SynthesisFrontiers in public health2026

Prevalence and patterns of psychiatric comorbidities in type 2 diabetes mellitus: a systematic review and meta-analysis.

Muhanad Saleh Alzahrani, Abdullah Alabbasi, Ziyad Alzahrani, Turki Alsafrani

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhanad Saleh AlzahraniJeddah First Cluster, Joint Program of Family Medicine Jeddah, Jeddah, Saudi Arabia.
Abdullah AlabbasiJeddah First Cluster, Joint Program of Family Medicine Jeddah, Jeddah, Saudi Arabia.
Ziyad AlzahraniCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Turki AlsafraniDepartment of Orthopedic Surgery, Saudi German Hospital Jeddah, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a global health challenge that is frequently complicated by psychiatric comorbidities, which can worsen disease outcomes and quality of life. Accurate prevalence estimates are essential to inform integrated management strategies. Objective: This study aimed to systematically review and meta-analyze the prevalence and patterns of psychiatric comorbidities in individuals with T2DM. Methods: A comprehensive search of PubMed, ScienceDirect, Google Scholar, and the Cochrane Library was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies included full-text, peer-reviewed articles reporting psychiatric comorbidities in adults with T2DM. Data extraction was performed independently by two reviewers. Pooled prevalence estimates were calculated using a random effects model, with heterogeneity assessed using the I Results: A total of 12 studies met the inclusion criteria. The pooled prevalence of depression in adults with T2DM was 19% (95% CI: 14-24%), based on eight contributing studies. Mild cognitive impairment (MCI) was also frequently observed, with a pooled prevalence of 39% (95% CI: 23-59%) across four studies. Considerable variability among studies was evident, likely attributable to differences in study design, diagnostic methods, sampling frames, and population characteristics. Conclusion: Psychiatric comorbidities are highly prevalent in individuals with T2DM, particularly depression and cognitive impairment, emphasizing the need for integrated psychiatric and metabolic care. This meta-analysis demonstrates that psychiatric comorbidities, particularly depression and cognitive impairment, are common in individuals with T2DM, highlighting the need for routine psychiatric screening and integrated diabetes care.

Indexed as

Diabetes Mellitus, Type 2Mental DisordersComorbidityHumansPrevalencecognitive impairmentdepressionmeta-analysisprevalencepsychiatric comorbiditiesschizophreniatype 2 diabetes mellitus

Identifiers

PMID41783697
PMCPMC12953136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.