Minimal intraoperative anticoagulation strategy for lung transplantation with preoperative heparin-induced thrombocytopenia.

Neelesh Bagrodia, Ammu V Alvarez, Doug A Gouchoe, Bryan A Whitson, Matthew C Henn, Kukbin Choi

Abstract readCase Reports

In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Neelesh BagrodiaDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Ammu V AlvarezDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Doug A GouchoeDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Bryan A WhitsonDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Matthew C HennDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Kukbin ChoiDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heparin-induced thrombocytopenia (HIT) in patients on mechanical circulatory support (MCS) prior to lung transplantation poses a unique challenge of balancing thrombotic versus hemorrhagic complications. An alternative method of anticoagulation is bivalirudin, offering advantages of rapid titration and a short half-life. We present 2 cases of patients on MCS who developed HIT and were anticoagulated with bivalirudin preoperatively. Contingent on whether additional cannulation was required at the time of lung transplantation, bivalirudin was held either at incision or after cannulation. Both patients were successfully transplanted without coagulopathic complications.

Indexed as

AnticoagulationHeparin-induced thrombocytopeniaLung transplantationMechanical circulatory support

Identifiers

PMID41783607

DOI10.1016/j.jhlto.2026.100517

PMCPMC12954324

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.