Evidence map›Paper›PMID 41783566›Full record

ArticleMarine life science & technology2026

The sterols-LXR axis alleviates IL-17-mediated acute inflammatory response in

Si Zhu, Zhimeng Lv, Jiqing Liu, Yanrong Li, Chenghua Li

Abstract read
In one paragraph

Article in Marine life science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Si ZhuState Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo, 315211 China.
Zhimeng LvState Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo, 315211 China.
Jiqing LiuState Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo, 315211 China.
Yanrong LiNingbo Institute of Oceanography, Ningbo, 315832 China.
Chenghua LiState Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo, 315211 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation plays a crucial role in defending the host against pathogens and other harmful stimuli. However, uncontrolled acute inflammation has been implicated in a multitude of diseases, including those that affect aquatic animals. While the processes that initiate the inflammatory response are relatively well understood, the roles of lipids, their derivatives, and the mechanisms by which they contribute to alleviating acute inflammation remain less well characterized. In the present study, lipidomic analyses were performed to identify changes in lipid metabolism in the coelomocytes of the sea cucumber Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-025-00322-9.

Indexed as

Acute inflammationAlleviationIL-17LXRSterols

Identifiers

PMID41783566
PMCPMC12953810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.