General transcription factor IIIAa regulates the transcription of somatic 5S rRNA and influences embryonic organ development in zebrafish.

Junzhi Luo, Binbin Tao, Ji Chen, Yanlong Song, Wei Hu

Abstract read

In one paragraph

Article in Marine life science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Inherited human TFIIIA deficiency disrupts T cell development.medRxiv : the preprint server for health sciences · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junzhi LuoKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture and College of Fisheries, Huazhong Agricultural University, Wuhan, 430070 China.

Binbin TaoState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, National Aquatic Biological Resource Center, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072 China.

Ji ChenState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, National Aquatic Biological Resource Center, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072 China.

Yanlong SongState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, National Aquatic Biological Resource Center, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072 China.

Wei HuKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture and College of Fisheries, Huazhong Agricultural University, Wuhan, 430070 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factor IIIA (TFIIIA) is a zinc finger protein that facilitates the assembly of a transcription complex by recruiting transcription factors TFIIIB and TFIIIC, along with RNA polymerase III, to initiate the transcription of 5S rRNA genes. However, the effects of TFIIIA knockout in vertebrates remain unclear. To address this, we investigated the function of a homologous general transcription factor IIIAa, Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-025-00334-5.

Indexed as

5S rRNAgtf3aaOrgan developmentRibosomeZebrafish

Identifiers

PMID41783558

DOI10.1007/s42995-025-00334-5

PMCPMC12953832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.