Evidence map›Paper›PMID 41783540›Full record

ArticleInternational medical case reports journal2026

Anterior Uveitis in an HLA-B27 Positive Patient Following Influenza Vaccination.

Chenjie Pan, Anania Girma Woldetensaye, Dalia El Feky, Ngoc Trong Tuong Than, Amir Akhavanrezayat, Hansen Chen, Ming Yang, Shuai Yang, Ziyu Yu, Mengyun Hu and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International medical case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chenjie PanDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0001-8455-4905
Anania Girma WoldetensayeByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Dalia El FekyByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Ngoc Trong Tuong ThanByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Amir AkhavanrezayatByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Hansen ChenDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Ming YangByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Shuai YangDepartment of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Ziyu YuByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Mengyun HuInstitute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.
Hao YanDepartment of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA, USA.
Jia-Horung HungByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Quan Dong NguyenByers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report a case of acute anterior uveitis occurring shortly after influenza vaccination in a patient with HLA-B27 positivity, highlighting the potential role of genetic susceptibility in vaccine-related ocular inflammation. Case Summary: A 35-year-old Asian male experienced progressive unilateral ocular redness, pain, and blurred vision starting from three days after receiving the trivalent influenza vaccine. Ophthalmic examination afterwards demonstrated conjunctival injection, fine keratic precipitates, anterior chamber flare and cells, and posterior synechiae with normal intraocular pressure. Diagnostic workup was unremarkable except for HLA-B27 positivity. The patient was diagnosed with unilateral acute non-granulomatous anterior uveitis and successfully treated with topical corticosteroids and cycloplegics, with resolution of inflammation and no recurrence over six months of follow-up. Conclusions and Importance: The index report highlights that HLA-B27 positive individuals may be particularly vulnerable to diverse systemic triggers, including vaccines.

Indexed as

autoimmune diseaseHLA-B27influenza vaccinationuveitis

Identifiers

PMID41783540
PMCPMC12953243

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.