Evidence map›Paper›PMID 41783461›Full record

ArticlePNAS nexus2026

Extremophile survives the transient pressures associated with impact-induced ejection from Mars.

Lily Zhao, Cesar A Perez-Fernandez, Jocelyne DiRuggiero, K T Ramesh

Abstract read
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lily ZhaoDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0009-0000-7299-3935
Cesar A Perez-FernandezDepartment of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0000-0002-5569-6039
Jocelyne DiRuggieroDepartment of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0000-0001-6721-8061
K T RameshDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0000-0003-2659-4698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large-scale impacts are ubiquitous in the solar system, and the likelihood of survival of organisms after an impact event plays a key role in planetary protection, the search for extraterrestrial life, and the assessment of the panspermia hypothesis. Impacts generate very high stresses for short times, resulting in extreme pressures and high rates of loading. Can microorganisms survive such extreme conditions? Directly assessing the resilience of microorganisms subjected to impact stresses has been difficult because of challenges in experimental design for these extreme conditions, together with the choices of biological model system. Here, we describe an experimental approach that allows us to subject microorganisms to controlled extreme pressures for short times, recover these impacted microorganisms, and then assess their rates of survival, structural damage, and their molecular response to these extreme events. We focused on

Indexed as

biological response mechanismsextremophilesimpact ejectaplanetary impact

Identifiers

PMID41783461
PMCPMC12954678

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.