Evidence map›Paper›PMID 41783373›Full record

ArticleClinical and translational radiation oncology2026

ESTRO consensus guidelines on GTV delineation and dose-escalation in rectal cancer.

Giuditta Chiloiro, Angela Romano, Regina Beets-Tan, Krzysztof Bujko, Davide Cusumano, Emmanouil Fokas, Karin Haustermans, Florence Huguet, Martijn Pw Intven, Corrie Am Marijnen and 6 more

Abstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giuditta ChiloiroFondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Angela RomanoFondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Regina Beets-TanDepartment of Diagnostic Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
Krzysztof BujkoDepartment of Radiotherapy I, M. Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Davide CusumanoMater Olbia Hospital, Olbia, Sassari, Italy.
Emmanouil FokasDepartment of Radiation Oncology, Cyberknife and Radiotherapy, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Faculty of Medicine Cologne, University Hospital Cologne, Cologne, Germany.
Karin HaustermansDepartment of Radiation Oncology, University Hospitals Leuven 3000 Leuven, Belgium.
Florence HuguetService d'oncologie radiothérapie, hôpital Tenon, AP-HP, Sorbonne université, Paris, France.
Martijn Pw IntvenDepartment of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
Corrie Am MarijnenDepartment of Radiation Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Ilaria NacciFondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Iris D NagtegaalDepartment of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Femke P PetersDepartment of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Alexandra StewartRoyal Surrey Hospital, NHS Foundation trust, Guildford, United Kingdom.
Vincenzo ValentiniCentro Eccellenza Oncologia e Diagnostica per Immagini, Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy.
Maria Antonietta GambacortaFondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Dose escalation, in rectal cancer, is defined as radiotherapy doses exceeding 54 Gy.•MRI-based GTV definition is central to dose-escalated rectal cancer RT.•Dose escalation supports organ preservation in selected rectal cancer patients.•Delphi methodology achieved consensus across key clinical and imaging domains.

Identifiers

PMID41783373
PMCPMC12954289

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.