Evidence map›Paper›PMID 41783357›Full record

ArticleMolecular therapy. Oncology2026

Enhancing cancer killing and natural killer cell persistence by targeting NOXA, a predictor of poor patient survival.

Sung-Bae Kang, Ji Hye Jeong, Seung Wook Kim, Hyejin Yoo, Seunghun Lee, Ji-Hye Oh, Chang Ohk Sung, Seung-Hwan Lee, Eunsung Jun, Mihue Jang

Abstract read
In one paragraph

Article in Molecular therapy. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sung-Bae KangMedicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Ji Hye JeongDepartment of Convergence Medicine, Asan Institute for Life Sciences, University of Ulsan College of Medicine and Asan Medical Center, Seoul 05505, Republic of Korea.
Seung Wook KimMedicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Hyejin YooMedicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Seunghun LeeAdvanced Bio and Healthcare Materials Research Division, Korea Institute of Materials Science, Changwon 51508, Republic of Korea.
Ji-Hye OhBioinformatics Core Laboratory, Convergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea.
Chang Ohk SungBioinformatics Core Laboratory, Convergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea.
Seung-Hwan LeeDepartment of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Eunsung JunDepartment of Convergence Medicine, Asan Institute for Life Sciences, University of Ulsan College of Medicine and Asan Medical Center, Seoul 05505, Republic of Korea.
Mihue JangMedicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK)-cell-based therapeutics have emerged as promising modalities in cancer immunotherapy due to their potent ability to target and kill cancer cells. However, their clinical efficacy is often constrained by the limited

Indexed as

apoptosisCRISPR/Cas9metabolic activityMT: Regular IssueNK cellNOXA

Identifiers

PMID41783357
PMCPMC12955672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.