Evidence map›Paper›PMID 41783333›Full record

ArticleArthroplasty today2026

Popliteal Artery Injury Risk in Total Knee Arthroplasty Related to Anatomic Variations: A Scoping Review.

Hiren Parekh, Bohdanna Zazulak, Adam V Daniel, Kinjal Vasavada, Elie Mansour, Michael Medvecky

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Article in Arthroplasty today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hiren ParekhYale College, Yale University, New Haven, CT, USA.
Bohdanna ZazulakDepartment of Orthopaedic Surgery, Yale School of Medicine, New Haven, CT USA.
Adam V DanielDepartment of Orthopedic Surgery, Orlando Health Jewett Orthopedic Institute, Orlando, FL, USA.
Kinjal VasavadaDepartment of Orthopaedic Surgery, Yale School of Medicine, New Haven, CT USA.
Elie MansourDepartment of Orthopaedic Surgery, Yale School of Medicine, New Haven, CT USA.
Michael MedveckyDepartment of Orthopaedic Surgery, Yale School of Medicine, New Haven, CT USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Popliteal artery (PA) injury during total knee arthroplasty (TKA) is rare but can lead to devastating complications, including PA repair or bypass, limb ischemia, compartment syndrome, fasciotomy, amputation, and death. Anatomical variations, such as high PA bifurcation or aberrant anterior tibial artery (ATA), may elevate this risk. Awareness of these variants during preoperative planning may reduce the likelihood of vascular injury and postoperative complications. This study aimed to assess the prevalence of PA anatomical variants, their relevance to TKA, and associated vascular complications. We hypothesized that aberrant arterial anatomy increases complication risk. Methods: A systematic literature search was conducted in EMBASE, MEDLINE, and Scopus in February 2025 using terms related to "aberrant popliteal artery," "anterior tibial artery anomaly," and "vascular complications in knee surgery." Studies were screened via Covidence. Inclusion criteria included the following: studies evaluating PA variation, prevalence, or TKA-associated vascular complications. Exclusion criteria included the following: non-English, abstracts, reviews, or unrelated studies. Extracted data included anatomical findings, imaging, and surgical outcomes. This study is compliant with Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews and Level of Evidence IV. Results: Of 5093 articles, 11 met inclusion criteria. Four case reports described vascular injuries during TKA in patients with aberrant PA anatomy (mean age 63 ± 18.2; 75% women). Imaging studies reported aberrant ATA prevalence ranging from 0.4% to 6%; one magnetic resonance imaging (MRI) study found a 3.2% prevalence in 280 knees. Proximity of the ATA to key landmarks increased injury risk, especially in women. Two cadaveric studies and 1 cohort study identified high PA bifurcations and variant ATA origins as risk factors. Conclusions: PA anatomical variation may be an underrecognized anomaly and be a risk factor for vascular injury during TKA. Awareness of the anatomical variation, careful review of pre-existing MRIs, and selective vascular imaging may improve surgical planning and help mitigate complications.

Indexed as

Anatomical variationAnterior tibial arteryOrthopaedic surgery complicationsPopliteal arteryTotal knee arthroplastyVascular injury

Identifiers

PMID41783333
PMCPMC12954335

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