Evidence map›Paper›PMID 41783229›Full record

ReviewSurgical neurology international2026

Perspective/short review: STAT surgery is the standard of care for treating significant spinal epidural abscesses.

Nancy E Epstein, Jamie Baisden, Marc A Agulnick

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nancy E EpsteinProfessor of Clinical Neurosurgery, School of Medicine, State University of NY at Stony Brook, NY, c/o Dr. Marc Agulnick 1122 Franklin Avenue Suite 106, Garden City, NY 11530, USA and Editor-in-Chief Surgical Neurology International.
Jamie BaisdenNeurosurgeon, USA.
Marc A AgulnickAssistant Clinical Professor of Orthopedics, NYU Langone Hospital Long Island, NY, USA, 1122 Franklin Avenue, Suite 106, Garden City, NY 11530, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Standard of Care (SOC) for treating significant spinal epidural abscesses (SEA) is STAT surgery for patients with the new-onset of neurological deficits following STAT contrast MR studies confirming significant neural (i.e. mild/moderate, moderate, or marked cord/nerve root) compression. Too many health care professionals, including physicians, and select spine surgeons still wrongly believe delaying "acute" spinal decompressions in patients with SEA for up to 8, 12, and even 24 hours is acceptable even in paralyzed patients. Methods: Here we review the fact that the standard of care for treating SEA is STAT surgery for patients demonstrating the new-onset of neurological deficits following STAT contrast MR scans confirming significant neural compression. Results: STAT surgery for newly neurologically symptomatic patients with SEA following STAT contrast MR scans documenting significant neural compression yields the best results. Notably, select patients without neural deficits or significant MR neural compression may be considered for non-surgical treatment. The "gold standard" for diagnosing SEA is the contrast MR, while non-contrast CT studies almost uniformly fail to diagnose SEA, and Myelogram-CT studies have significant limitations (i.e. risk of causing meningitis, and may fail to document cephalad extent of SEA if there is a distal total block to intrathecal contrast). Conclusion: STAT surgery is the SOC and treatment of choice for patient with SEA demonstrating significant new-onset neurological deficits with significant STAT contrast MR findings of neural compression. Further, STAT means STAT, no waiting period is acceptable (i.e. 8, 12 or up to < 24 hours) particularly in paralyzed patients.

Indexed as

Best OutcomesContrast MR StudiesEarly Surgery < 0-24 HoursFailure of CTLimitations/Risks of Myelogram-CT (MCT) only if MR not feasibleMR Gold StandardNew- Onset Neurological DeficitsSignificantSpinal Cord/Nerve Root CompressionSpinal Epidural Abscesses (SEA)Standard of Care (SOC)

Identifiers

PMID41783229
PMCPMC12954256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.