Evidence map›Paper›PMID 41783197›Full record

ArticleSurgical neurology international2026

Treatment-related complications of intracranial aneurysms smaller than 5 mm: A multicenter analysis of 1,519 cases in Latin America.

Alejandra Jaume, Pedro Lylyk, Pablo Rubino, Jorge Mura, Daniel Mantilla, German Abdo, Carlos Bleise, Juan Mejia, Laura Campaña, Ivan Lylyk and 11 more

Abstract read
In one paragraph

Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

21 authors.

Alejandra JaumeNeurosurgery Service of Maciel Hospital, and Vascular Interventional Center of American Clinic, Montevideo, Uruguay.
Pedro LylykSacred Family Clinic, Buenos Aires, Argentina.
Pablo RubinoGerman Hospital, Buenos Aires, Argentina.
Jorge MuraThe Condes Clinic, Santiago de Chile, Chile.
Daniel MantillaFaculty of Health Sciences, Universidad Autónoma de Bucaramanga, and FOSCAL Clinic, Bucaramanga, Colombia.
German AbdoNeurointervention Center, Axxis Hospital, and Eugenio Espejo Specialty Hospital, Quito, Ecuador.
Carlos BleiseSacred Family Clinic, Buenos Aires, Argentina.
Juan MejiaSanta Fe Foundation University Hospital of Bogotá, Colombia.
Laura CampañaSanta Fe Foundation University Hospital of Bogotá, Colombia.
Ivan LylykSacred Family Clinic, Buenos Aires, Argentina.
Clara MartinGerman Hospital, Buenos Aires, Argentina.
Camilo AlvaradoFaculty of Health Sciences, Universidad Autónoma de Bucaramanga, and FOSCAL Clinic, Bucaramanga, Colombia.
Matias NegrottoNeurosurgery Service of Maciel Hospital, and Vascular Interventional Center of American Clinic, Montevideo, Uruguay.
Mariana RomeroNeurosurgery Service of Maciel Hospital, and Vascular Interventional Center of American Clinic, Montevideo, Uruguay.
Julio QuispeNeurointervention Center, Axxis Hospital, and Eugenio Espejo Specialty Hospital, Quito, Ecuador.
Nicolas InzunzaThe Condes Clinic, Santiago de Chile, Chile.
P Nicolas LylykSacred Family Clinic, Buenos Aires, Argentina.
Laura OlarteSanta Fe Foundation University Hospital of Bogotá, Colombia.
Silvina MartinezGerman Hospital, Buenos Aires, Argentina.
Maria EstevezFaculty of Health Sciences, Universidad Autónoma de Bucaramanga, and FOSCAL Clinic, Bucaramanga, Colombia.
Juan GilDepartment of Quantitative Methods, Faculty of Medicine, Uruguay.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Small (<5 mm) intracranial aneurysms present a therapeutic challenge due to their low annual rupture risk and uncertainties regarding procedure-related morbidity. Evidence from Latin America remains limited. Methods: We conducted a retrospective multicenter observational study including 1,519 patients treated between 2017 and 2023 in eight referral centers across five Latin American countries. Demographic, clinical, morphological, and treatment-related variables were analyzed. Logistic regression was used to identify independent predictors of treatment-related complications. Results: The overall complication rate was 6%. Surgical treatment showed higher crude complication rates (11%) compared with endovascular therapy (6%), largely reflecting a greater proportion of ruptured aneurysms. Independent predictors of treatment-related complications were a history of aneurysmal subarachnoid hemorrhage (odds ratio [OR] = 5.03), intraparenchymal hematoma before treatment (OR = 3.56), and ruptured aneurysm status (OR = 2.13). Complications were associated with higher mortality (31% vs. 7%; Conclusion: In this first regional multicenter series, treatment of small intracranial aneurysms in Latin America demonstrated low complication rates and favorable safety profiles for both surgical and endovascular techniques. The predictors identified may support clinical decision-making and improve prognostic assessment.

Indexed as

ComplicationsEndovascular proceduresIntracranial aneurysmNeurosurgical proceduresSubarachnoid hemorrhage

Identifiers

PMID41783197
PMCPMC12954230

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.