Evidence map›Paper›PMID 41782903›Full record

ArticlePhysics and imaging in radiation oncology2026

Reduced beam time and distal linear energy transfer with mini-ridge filters in pencil beam scanning proton therapy.

Fionnbarr O'Grady, Lisa Stephenson, Martin Janson, Avani D Rao, Ashish K Chawla, Jiajin Fan, Peng Wang

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fionnbarr O'GradyInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.
Lisa StephensonInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.
Martin JansonRaySearch Laboratories, Eugeniavägen 18, 113 68 Stockholm, Sweden.
Avani D RaoInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.
Ashish K ChawlaInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.
Jiajin FanInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.
Peng WangInova Schar Cancer Institute, Inova Health System, 8081 Innovation Park Dr, Fairfax, VA 22031, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Previous studies have demonstrated that mini-ridge filters (MRF) can reduce beam delivery time in pencil beam scanning (PBS) proton therapy, but the effect on plan quality has not been analyzed in detail. Furthermore, the range modulation produced by the MRF may lead to an added benefit of reduced dose-averaged linear energy transfer (LET Materials and methods: Twenty patient plans from a range of treatment sites, including five deep inspiration breath hold (DIBH) patients, have been re-optimized with a Monte Carlo based MRF beam model and compared to the corresponding clinical plans in beam delivery time, clinical acceptability, and a range of dose and LET Results: The average delivery time per beam decreased from (96.7 ± 4.9) s to (75.3 ± 4.0) s (p < 0.001). DIBH patients saw a reduction from (82.8 ± 15.5) s to (70.4 ± 12.7) s. The average reduction in maximum LET Conclusions: MRFs can be used in PBS proton therapy to achieve a clinically relevant reduction in beam delivery time, and distal LET

Indexed as

Beam delivery timeLETMini-ridge filterProton therapy

Identifiers

PMID41782903
PMCPMC12955685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.