ArticleSage open pediatrics
Predictors of Mortality Among Pediatric Patients Admitted to Intensive Care Units in Eastern Amhara, Ethiopia: A Prospective Multi-Center Cohort Study.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Ethiopia remains among the 5 countries with the highest under-five mortality, yet prospective multicenter data on pediatric intensive care unit (PICU) outcomes are limited. Objective: To determine the incidence and predictors of mortality among children admitted to PICUs in Eastern Amhara. Methods: A prospective observational study was conducted on 240 children admitted to tertiary-level PICUs between February and April 2025. Kaplan-Meier analysis estimated survival probabilities, and Cox proportional hazards regression identified independent predictors of mortality. Results: Fifty-eight deaths (24.2%) occurred. Rural residence (AHR: 2.0, 95% CI: 1.2-3.5), the use of inotropic agents (AHR: 2.0, 95% CI: 1.2-3.5) consciousness level (GCS <8; AHR: 2.3, 95% CI: 1.2-4.4), presence of comorbidities (AHR: 1.9, 95% CI: 1.1-3.4) were associated increased mortality. Conclusion: PICU mortality was high, especially among rural children, those with severe neurological impairment, comorbidities, or requiring inotropes, emphasizing early identification and close monitoring of high-risk patients.
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