Evidence map›Paper›PMID 41782664›Full record

ArticleAllergologie select2026

Potential infliximab-induced Kounis syndrome in a patient with metastatic melanoma.

Corsin Seeli, Dimitri Patriki, Omar Hasan Ali, Ann-Kathrin Blumenröther, Marie-Charlotte Brüggen, Andrea Nolting, Carole Guillet

Abstract readCase Reports
In one paragraph

Article in Allergologie select, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corsin SeeliDepartment of Dermatology, and.
Dimitri PatrikiDepartment of Cardiology, University Hospital Zurich, Switzerland.
Omar Hasan AliDepartment of Dermatology, and.
Ann-Kathrin BlumenrötherDepartment of Dermatology, and.
Marie-Charlotte BrüggenDepartment of Dermatology, and.
Andrea NoltingDepartment of Dermatology, and.
Carole GuilletDepartment of Dermatology, and.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKounis syndrome is a rare type of allergic or hypersensitivity-induced acute coronary syndrome. The release of numerous inflammatory mediators induces vasospasms and potential thrombosis leading to myocardial infarction. CASE HISTORY: We present the case of a 65-year-old woman with metastatic melanoma who experienced chest tightness and dyspnea after her 3

conclusionThis case highlights the importance of considering Kounis syndrome as a potentially life-threatening complication during monoclonal antibody infusion, even in the absence of a prior allergic history and typical skin manifestations. Early recognition and treatment are crucial and spared our patient further invasive diagnostical and therapeutical interventions.

Indexed as

acute coronary syndromeimmune-mediated reactioninfliximabKounis syndromemast cell activationmonoclonal antibody hypersensitivity

Identifiers

PMID41782664
PMCPMC12955525

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.