Evidence map›Paper›PMID 41782655›Full record

ArticleHealth science reports2026

An Updated Narrative Review on the Therapeutic Potential of Resveratrol in the Treatment of Cancer.

Mohammad Ashraful Islam, Al Amin, Md Abdul Aziz, Md Mahabubur Rahaman, Jakir Hossain, Jakir Ahmed Chowdhury, Mohammad Safiqul Islam

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad Ashraful IslamDepartment of Pharmacy University of Asia Pacific Dhaka Bangladesh.ORCID https://orcid.org/0009-0008-8042-663X
Al AminDepartment of Pharmacy, Faculty of Pharmacy University of Dhaka Dhaka Bangladesh.ORCID https://orcid.org/0009-0008-8552-743X
Md Abdul AzizDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.ORCID https://orcid.org/0000-0003-2079-4509
Md Mahabubur RahamanDepartment of Computer Information Systems American International University Dhaka Bangladesh.ORCID https://orcid.org/0009-0001-9479-4811
Jakir HossainDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.ORCID https://orcid.org/0009-0007-9568-9267
Jakir Ahmed ChowdhuryDepartment of Pharmaceutical Technology Faculty of Pharmacy, University of Dhaka Dhaka Bangladesh.ORCID https://orcid.org/0000-0002-4274-5997
Mohammad Safiqul IslamDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.ORCID https://orcid.org/0000-0003-4924-5319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongoing research to find suitable and effective sensitizers. Resveratrol, a natural polyphenolic compound, has demonstrated significant effects in inhibiting the growth and spread of cancer. However, the molecular mechanisms and applications of resveratrol remain unclear. Objective: In this updated narrative review, we aimed at discussing the role and related molecular mechanisms of resveratrol in various cancers and providing an overview of its therapeutic potential for the treatment and prevention of these cancers. Methodology: We conducted an extensive literature search across four major databases, including PubMed, Google Scholar, Web of Science, and ScienceDirect, to identify all relevant articles. Result: Resveratrol is a naturally occurring polyphenolic compound, specifically a stilbene, found in significant quantities in grapes, berries, peanuts, and various other plants. Resveratrol significantly contributes to the reduction of various human cancers, including those of the breast, cervix, thyroid, prostate, brain, skin, colon, bone, and ovarian cancers. Resveratrol has been shown to influence cell cycle arrest, activate apoptosis, and suppress metastasis, all of which are achieved through various signaling pathways. Additionally, several in vivo studies have shown promising results suggesting it may reduce tumor development and extend lifespan in animal cancer models, among other benefits. Conclusion: This review indicates that resveratrol could serve as a prototype for developing more efficacious and less toxic therapeutic agents for the treatment of various cancers.

Indexed as

apoptosiscancerchemopreventive agentpreventionresveratrol

Identifiers

PMID41782655
PMCPMC12953729

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.