Evidence map›Paper›PMID 41782621›Full record

Observational studyJNMA; journal of the Nepal Medical Association2025

Drug Poisonings among Patients Presenting to the Emergency Department of a Tertiary Care Center in Eastern Nepal: An Observational Study.

Namita Kumari Mandal, Rabin Bhandari, Gajendra Prasad Rauniyar, Madan Krishna Mandal

Abstract readObservational Study
In one paragraph

Observational study in JNMA; journal of the Nepal Medical Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Namita Kumari MandalDepartment of Clinical Pharmacology and Therapeutics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
Rabin BhandariDepartment of General Practices and Emergency Medicine, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
Gajendra Prasad RauniyarDepartment of Clinical Pharmacology and Therapeutics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
Madan Krishna MandalDepartment of Emergency Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Morang, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Drug poisoning is a major public health concern contributing to emergency visits and hospital admissions. Understanding the patterns and characteristics of drug poisoning cases is crucial for developing targeted prevention strategies, improving early recognition, guiding appropriate clinical management, and informing public health policies to reduce morbidity and mortality. This study aimed to determine the prevalence and pattern of drug poisoning cases presenting to the Emergency Department of a tertiary care center in Eastern Nepal. Methods: A prospective observational study was conducted in the Emergency Department of a tertiary care hospital from 1 January to 31 December 2022, after ethical approval (Ref. No: IRC/1466/018). Data from 60 eligible patients were collected using a structured proforma including socio-demographics, type and route of drug exposure, intent (accidental or suicidal), time of presentation, clinical features, management, and short-term outcomes. Descriptive statistics were used for analysis. Results: Among 30,019 emergency admissions, 60 (0.20%) were due to drug poisoning, with 38 (63.33%) cases accounting for females. Intentional self-poisoning occurred in 59 (98.33%) cases, while 1 (1.67%) case was accidental. Among the reported cases, 21 (35.00%) cases involved the use of CNS depressants (benzodiazepines), 18 (30.00%) cases involved analgesics, and 2 (3.33%) cases involved antidepressant use. There were 13 (21.76%) patients who presented within six hours of ingestion and received timely supportive care. There was 1 (1.67%) case of mortality. Conclusions: Intentional self-poisoning was the predominant form of drug poisoning, mainly involving benzodiazepines and analgesics among young females. Most patients recovered with supportive management, and the case fatality rate was low.

Indexed as

Drug OverdoseEmergency Service, HospitalPoisoningAdolescentAdultBenzodiazepinesEmergency Room VisitsFemaleHumansMaleMiddle AgedNepalPrevalenceProspective StudiesSuicide, AttemptedTertiary Care CentersBenzodiazepinesanalgesicsbenzodiazepinesdrug poisoningintentional self-poisoning

Identifiers

PMID41782621
PMCPMC12906720

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.