ArticleKorean journal of family medicine2026
The cutoff value of serum triglyceride/high-density lipoprotein cholesterol ratio of high pericardial adipose tissue in Korean: a retrospective study.
Article in Korean journal of family medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Recently, the triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio and pericardial adipose tissue (PAT) have emerged as important indicators of metabolic syndrome (MS). We aimed to evaluate the relationship between the TG/HDL ratio and PAT. Methods: We retrospectively analyzed the data of 627 patients who underwent coronary multidetector computed tomography to assess metabolic parameters. Subjects were stratified into two groups based on the PAT volume cutoff associated with MS, specifically 142.2 cm3, and metabolic parameters were compared between these groups. The TG/HDL ratio was divided into tertiles according to the logarithm of TG/HDL, and differences in PAT-related parameters among the tertiles were assessed using analysis of variance. Logistic regression was performed to estimate the odds ratios (ORs) for high PAT (≥142.2 cm3) across tertiles and receiver operating characteristic (ROC) analysis was performed to determine the optimal TG/HDL ratio cutoff for linking with high PAT. Results: The mean TG/HDL ratio in the high PAT group was 3.6. The TG/HDL ratio demonstrated a strong positive correlation with several metabolic parameters. Individuals in the higher log (TG/HDL) tertiles exhibited a greater prevalence of metabolic disturbances, including increased PAT, and displayed higher ORs for high PAT (second tertile OR, 3.51; third tertile OR, 3.26) after adjusting for age, sex, smoking, hypertension, type 2 diabetes, and dyslipidemia status. ROC analysis identified a TG/HDL ratio of 1.918 (P<0.001) as the threshold for elevated PAT levels. Conclusion: The TG/HDL ratio was positively correlated with high PAT volume, and the TG/HDL ratio cutoff for association with high PAT was determined to be 1.918.
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