Evidence map›Paper›PMID 41782279›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2026

Shifting paradigms in ICD tachytherapy deactivation in the final phase of life: eighteen years of perspective.

Ahmed A M Al Jaff, Anastasia D Egorova, Dilek Yilmaz, Martin J Schalij, Lieselot van Erven

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Article in European heart journal. Quality of care & clinical outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ahmed A M Al JaffDepartment of Cardiology, Leiden Heart-Lung Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Postbus 9600, Leiden 2300 RC, The Netherlands.ORCID 0009-0007-2971-6925
Anastasia D EgorovaDepartment of Cardiology, Leiden Heart-Lung Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Postbus 9600, Leiden 2300 RC, The Netherlands.ORCID 0000-0001-9312-2338
Dilek YilmazDepartment of Cardiology, Erasmus University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Martin J SchalijDepartment of Cardiology, Leiden Heart-Lung Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Postbus 9600, Leiden 2300 RC, The Netherlands.
Lieselot van ErvenDepartment of Cardiology, Leiden Heart-Lung Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Postbus 9600, Leiden 2300 RC, The Netherlands.ORCID 0000-0003-3882-9941

Funding

Abbott Medical Nederland BVBoston Scientific CorporationDepartment of Cardiology of the Leiden University Medical CenterEdwards Lifesciences
6 · The paper itself

Abstract

aimsImplantable cardioverter-defibrillators (ICDs) may deliver painful shocks in the final phase of life. The European Heart Rhythm Association (EHRA) and Heart Rhythm Society (HRS) recommend advanced care planning and timely tachytherapy deactivation to prevent this. This study aims to evaluate anticipatory tachytherapy deactivation practices over an 18-year period and identify implementation gaps to explore strategies for improvement. METHODS AND

resultsRecords of 1606 ICD or cardiac resynchronization therapy-defibrillator (CRT-D) patients (79% male; mean age 67 ± 10 years at implantation, 73 ± 10 at death) who died between 2006 and 2022 were reviewed. Heart failure (32%) and malignancy (15%) were the most common causes of death. Anticipatory tachytherapy deactivation occurred in 42% of patients. Deactivation rates increased 5.2% annually from 2006 to 2014 (P < 0.001), but plateaued from 2015 to 2022 (P = 0.403). Among deactivations, 33% occurred on the final day of life, mainly during hospitalization.

conclusionDespite improvements in anticipatory tachytherapy deactivation practices, a plateau has been reached. Many deactivations still occur on the final day of life, underscoring the need for earlier and more proactive counselling. Integrating deactivation discussions into routine care, particularly for heart failure patients, will be essential to ensure patient-centered advanced care planning.

Indexed as

Defibrillators, ImplantableHeart FailureTerminal CareAgedFemaleHumansMaleMiddle AgedRetrospective StudiesAdvance care planningDefibrillator shocksImplantable cardioverter-defibrillator (ICD)Palliative cardiologyTachytherapy deactivation

Identifiers

PMID41782279
PMCPMC13458154

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