Evidence map›Paper›PMID 41782183›Full record

Observational studyEuropean journal of neurology2026

Surgical Interventions in Idiopathic Intracranial Hypertension-A Comprehensive Multi-Center Study of Outcome and the Role of Treatment Indication.

Gabriel Bsteh, Nadja Skadkær Hansen, Sina Zaic, Steffen Hamann, Johanne Juhl Korsbæk, Nik Krajnc, Stefan Macher, Laleh Dehghani Molander, Klaus Novak, Therese Wallentin Steenfos and 4 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gabriel BstehDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Nadja Skadkær HansenDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark.ORCID 0000-0002-5488-7992
Sina ZaicDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Steffen HamannDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark.
Johanne Juhl KorsbækDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark.
Nik KrajncDepartment of Neurology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-4146-5870
Stefan MacherDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Laleh Dehghani MolanderDepartment of Ophthalmology, Odense University Hospital, Odense, Denmark.
Klaus NovakComprehensive Center for Clinical Neurosciences & Mental Health, Medical University of Vienna, Vienna, Austria.
Therese Wallentin SteenfosDepartment of Neurology, Odense University Hospital, Odense, Denmark.
Marianne WegenerDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark.
Berthold PempDepartment of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Rigmor Højland JensenDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark.ORCID 0000-0001-6433-5887
Dagmar BeierDepartment of Neurology, Odense University Hospital, Odense, Denmark.

Funding

Medical Scientific Fund of the Mayor of the City of Vienna Project 21009
6 · The paper itself

Abstract

backgroundSurgical intervention is recommended in idiopathic intracranial hypertension (IIH) for fulminant or treatment-refractory cases, yet data on outcomes remain limited, particularly regarding indication-specific effects. This study evaluated outcomes and indications for surgery in IIH, aiming to identify predictors of favorable or adverse results.

methodsA retrospective multi-center study was conducted by the Danish-Austrian IIH Consortium (DASH-IIH). Databases from three centers (Vienna, Odense, Copenhagen) were screened for persons with IIH (pwIIH) fulfilling revised Friedman criteria who underwent surgery and had ≥ 6 months of follow-up. Outcomes at 6 months included visual function, headache improvement (≥ 50%), papilledema resolution, and severe adverse events. Multivariable regression was used to adjust for confounders.

resultsOf 1310 pwIIH, only 3.6% required surgery overall. Thirty-six pwIIH were included (100% female; mean age 32.5 years; median BMI 37.0; median CSF opening pressure 41 cmH

conclusionCSF diversion and ONSF are effective in IIH with acute visual threat, improving vision and, to a much lesser extent, headache. Refractory headache alone appears insufficient indication for surgical intervention.

Indexed as

Neurosurgical ProceduresPseudotumor CerebriAdultFemaleHumansMaleMiddle AgedPapilledemaRetrospective StudiesTreatment OutcomeYoung Adultidiopathic intracranial hypertensionindicationoptic nerve sheath fenestrationshuntsurgery

Identifiers

PMID41782183
PMCPMC12960284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.