Evidence map›Paper›PMID 41782106›Full record

ArticleBMC infectious diseases2026

Chlamydia trachomatis infection seroprevalence among women with normal and abnormal cervical smears and its implication for Nigerian cervical cancer screening.

Tochukwu Dickson Ifezuoke, Monique Iheoma Ajah, Leonard Ogbonna Ajah, Hyginus Uzo Ezegwui, Amaechi Okwudili, Victor Chinazo Duru, Amara Ann Ifezuoke, Ifeanyi John Achara

Abstract read
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Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tochukwu Dickson IfezuokeGynaecological Oncology Unit, Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Monique Iheoma AjahInstitute of Maternal and Childhealth, University of Nigeria, Ituku-Ozalla Campus, Enugu, Nigeria.
Leonard Ogbonna AjahGynaecological Oncology Unit, Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria. leonard.ajah@unn.edu.ng.
Hyginus Uzo EzegwuiGynaecological Oncology Unit, Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Amaechi OkwudiliDepartment of Haematology and Immunology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Victor Chinazo DuruGynaecological Oncology Unit, Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Amara Ann IfezuokeDepartment of Nursing Sciences, University of Nigeria, Enugu Campus, Enugu, Nigeria.
Ifeanyi John AcharaGynaecological Oncology Unit, Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe oncogenic human papilloma virus (HPV) causes transient infections of the cervix, hence other co-factors can potentiate the formation of cervical epithelial cell abnormalities. This study was aimed at determining the seroprevalence of Chlamydia trachomatis infection among women with normal and abnormal Papanicolaou smear cytology results.

methodsThis was a hospital-based cross-sectional comparative study in which study participants were conveniently recruited from January to June,2021. The 50 cases and 50 controls were women with abnormal and normal Papanicolaou smear cytology results respectively. Both groups had blood samples collected for anti- Chlamydia trachomatis antibody test. The data was analyzed with the Statistical Product and Service Solutions (IBM SPSS, Armonk, New York, USA) version 24.0 for windows. The categorical and continuous variables were analyzed with chi square(X

resultsThe overall seroprevalence of Chlamydia trachomatis infection was 27%. Positive Chlamydia infection had a significant association with cervical epithelial cell abnormalities (P- value = 0.001). Positive history of multiple sexual partners and coitarche at age of < 18 years were associated factors for Chlamydia trachomatis infection.

conclusionThis study identified an association between history of Chlamydia trachomatis infection and cervical epithelial cell abnormalities.

Indexed as

Chlamydia InfectionsChlamydia trachomatisUterine Cervical NeoplasmsAdultAntibodies, BacterialCervix UteriCross-Sectional StudiesEarly Detection of CancerFemaleHumansMiddle AgedNigeriaPapanicolaou TestSeroepidemiologic StudiesVaginal SmearsYoung AdultAntibodies, BacterialCervical cytologyChlamydia trachomatisEnuguScreening

Identifiers

PMID41782106
PMCPMC13069745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.