Evidence map›Paper›PMID 41782093›Full record

ArticleBMC geriatrics2026

Development and validation of a deep vein thrombosis risk assessment tool for surgical patients aged 75 years and older.

Heqing Ye, Jingru Li, Libing Du, Chengtai Li, Rongzhu Chen

Abstract readValidation Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Heqing Ye *Department of Operating Room, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province, 230001, China.
Jingru Li *Department of Operating Room, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province, 230001, China.
Libing DuDepartment of Operating Room, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province, 230001, China.
Chengtai LiDepartment of Operating Room, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province, 230001, China.
Rongzhu ChenDepartment of Operating Room, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province, 230001, China. 13705601495@139.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep vein thrombosis (DVT) is a common and severe medical condition characterized by the formation of thrombi in deep veins, primarily affecting older surgical patients. The present study aimed to identify risk factors for DVT in surgical patients aged 75 years and older and subsequently develop and validate a risk assessment tool for this patient population.

methodsA retrospective study was conducted on surgical patients (n = 686) aged 75 years and older at a tertiary general hospital in Hefei, China, from January to December 2024. Predictors for the model were selected using Least Absolute Shrinkage and Selection Operator (LASSO) regression, followed by multivariable logistic regression. Area under the curve, calibration curve, and decision curve analysis (DCA) were used to examine the discriminative power, calibration, and clinical efficacy of the predictive models. Internal validation was performed using both bootstrap resampling and 10-fold cross-validation.

resultsThe incidence of DVT among surgical patients aged 75 years and older was 14.7% (n = 101/686). Six predictors were identified and used to establish a nomogram: malignancy (OR: 7.590, 95% CI: 2.670–21.500), sex (OR: 0.387, 95% CI: 0.195–0.724), anesthesia duration (OR: 1.010, 95% CI: 1.006–1.014), D-dimer (OR: 1.210, 95% CI: 1.130–1.310), platelet count (OR: 1.010, 95% CI: 1.005–1.015), and pneumatic tourniquet application (OR: 2.700, 95% CI: 1.470–5.170). The nomogram demonstrated excellent discrimination (AUC = 0.786, 0.786 (95% CI, 0.738–0.834) and good calibration (Hosmer-Lemeshow test, P = 0.588). Upon interval validation, the model achieved a concordance index (C-index) of 0.791 (95% CI, 0.780–0.800). Finally, DCA demonstrated the net clinical benefit of this nomogram.

conclusionsThis study constructed a practical model to predict DVT in surgical patients aged 75 years and older. This model incorporates demographic characteristics and clinical risk factors, enabling individualized prediction.

Indexed as

Postoperative ComplicationsVenous ThrombosisAgedAged, 80 and overChinaFemaleHumansMaleNomogramsRetrospective StudiesRisk AssessmentRisk FactorsDeep vein thrombosisNomogramOlder surgical patientsPredictive model

Identifiers

PMID41782093
PMCPMC13069736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.