Evidence map›Paper›PMID 41781974›Full record

ReviewChinese medicine2026

44-year journey (1980-2024): scientometric insights into Sigesbeckiae herba and update on its medicinal properties and phytochemicals profile.

Parsa Dar, Cui Wenqing, Shaden A M Khalifa, Junming Chen, Kegang Linghu, Wei Xiong, Hesham R El-Seedi, Hua Yu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Parsa DarInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Macao, China.
Cui WenqingInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Macao, China.
Shaden A M KhalifaNeurology and Psychiatry and Department, Capio Saint Göran's Hospital, Sankt Göransplan 1, 112 19, Stockholm, Stockholm,, Sweden.
Junming ChenInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Macao, China.
Kegang LinghuThe High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province & School of Pharmaceutical Sciences, Guizhou Medical University, Guian New District, Guiyang, 561113, Guizhou, China.
Wei XiongSchool of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China.
Hesham R El-SeediDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, 42351, Madinah, Saudi Arabia. halsaeedi@iu.edu.sa.
Hua YuInstitute of Chinese Medical Sciences, State Key Laboratory of Mechanism and Quality of Chinese Medicine, University of Macau, Macao, China. bcalecyu@um.edu.mo.

Funding

Fundo para o Desenvolvimento das Ciências e da Tecnologia 005/2023/SKLUniversidade de Macau MYRG-GRG2023-00214-ICMS-UMDF; MYRG-GRG2024-00240-ICMS
6 · The paper itself

Abstract

This study uses Scientometric analysis to review Sigesbeckiae Herba (SH) research worldwide from 1980 to 2024. Data-driven analysis identifies patterns, partnerships, and possibilities. Due to its wide profile and traditional medical uses, SH is gaining attention, according to this research. China has made the most important contributions to SH research, followed by the United stated of America and Korea. Countries and organizations have not collaborated on SH research. We found "anti-inflammation," "rheumatic arthritis," and "NF-κβ" using keyword co-occurrence analysis. Citation analysis showed SH research's most prominent institutions, journals, and authors, offering a complete snapshot of organization and diffusion. The data shows that this subject has received substantial academic interest despite a reduction in publications since 2019. These findings highlight the need for cooperation, multidisciplinary methods, and attention to underrepresented disciplines for academics, funding organizations, and policymakers. SH has been used to cure inflammation. Sigesbeckia orientalis L., S. pubescens Makino, and S. glabrescens Makino are the primary botanical sources. This research extensively evaluates SH literature, focusing on its botanical properties, bioactive components, pharmacological effects, and probable toxicity. More than three hundred phytochemicals, including flavonoids, diterpenoids, sesquiterpenoids, oxylipins, and lignoids, were identified in the extract, many of which are known to exert diverse biological effects. The extracts of SH are used in traditional Chinese medicine (TCM) due to its immunomodulatory, anti-inflammatory, and anti-cancer activities and are being considered for cosmetics and skin issues. Pharmacological benefits of diterpenoids, sesquiterpenoids, and flavonoids are found. The study recommends further research and cooperation to enhance TCM and herbal research by comparing the chemical and pharmacological properties of these three SH species.

Indexed as

Anti-inflammatoryEnt-pimraneRheumatic arthritisScientometric analysisS. glabrescens MakinoSigesbeckiae HerbaSigesbeckia orientalis L.S. pubescens Makino

Identifiers

PMID41781974
PMCPMC12958691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.