Evidence map›Paper›PMID 41781750›Full record

ArticleTechniques in coloproctology2026

Clinical efficacy and failure-related factors of the loose-seton procedure combined with transanal opening of the intersphincteric space technique (LoSet-TROPlS) in the treatment of complex anal fistulas.

Qinghan Ma, Mengqing Dong, Hongwei Hua, Zhenyi Wang, Jiong Wu, Lei Jin

Abstract read
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Article in Techniques in coloproctology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qinghan MaDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0009-0004-7606-2862
Mengqing DongDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0009-0009-7595-5497
Hongwei HuaDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0009-0009-0814-7334
Zhenyi WangDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0000-0001-5653-9636
Jiong WuDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. tcmoctober9@163.com.ORCID 0000-0002-4756-3332
Lei JinDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 229198632@qq.com.ORCID 0000-0003-3361-6162

Funding

Changsha Wenxi Laser Medical Technology Co., Ltd. LY25013National Natural Science Foundation of China No.82004361Science and Technology Commission of Shanghai Municipality 20Y21901200Shanghai Institute of Traditional Chinese Medicine 24YJS14
6 · The paper itself

Abstract

objectiveTo observe the clinical efficacy of the loose-seton procedure combined with transanal opening of the intersphincteric space technique (LoSet-TROPlS) for complex anal fistulas.

methodsA retrospective analysis was conducted on the clinical data of 73 patients with cryptoglandular anal fistulas who underwent LoSet-TROPlS in our hospital from September 2020 to March 2021. The study evaluated the surgical healing rate, recurrence rate, time to seton removal, and postoperative anal incontinence.

resultsThe median follow-up time was 34.0 (32.0, 38.0) months. The primary healing rate was 83.56% (61/73), with a failure rate of 16.44% (12/73). The recurrence rate was 9.84% (6/61), and the overall healing rate was 86.30% (63/73). The median time for seton removal was 27 (23, 30) days. No patients experienced formed stool incontinence. Two patients occasionally had anal gas or fluid leakage, which improved after biofeedback therapy. Two patients experienced occasional mucous discharge. There was no statistically significant difference in anal canal and rectal pressure before and after surgery (P > 0.05).

conclusionsThe LoSet-TROPlS is an effective treatment for complex anal fistulas while preserving anal function. The procedure is not complicated and can be promoted for clinical application.

Indexed as

Anal CanalRectal FistulaSuture TechniquesAdultAgedColorectal Surgical ProceduresFecal IncontinenceFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsRecurrenceRetrospective StudiesTreatment FailureComplex anal fistulaLoose setonTransanal approach

Identifiers

PMID41781750
PMCPMC12966188

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.