Evidence map›Paper›PMID 41781708›Full record

ArticleNature metabolism2026

Extracellular CD44 lactylation impairs CD8

Yun Yang, Yong Wu, Xin Guo, Wen-Juan Gan, Wen-Xin Wu, Wei-Yi Shi, Xiao-Shun He, Yi-Xuan Liu, Shan Wan, Zhi Jiang and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yun Yang *Department of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Yong Wu *Department of General Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Xin Guo *Department of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Wen-Juan Gan *Department of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Wen-Xin Wu *Department of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Wei-Yi ShiDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Xiao-Shun HeDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yi-Xuan LiuDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Shan WanDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Zhi JiangDepartment of Biochemistry and Molecular Biology, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Yue LiuDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Xiu-Ming LiDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zu-Da PanDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Xue ZhangDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
You XuDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Xiao-Jiao GaoDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China.
Ling-Chuan GuoDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, China. szglc@hotmail.com.ORCID http://orcid.org/0000-0002-1028-9296
Guideng LiNational Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, China. lgd@ism.cams.cn.ORCID http://orcid.org/0000-0003-0840-7262
Hua WuDepartment of Pathology, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Soochow University, Suzhou, China. wuhua@suda.edu.cn.ORCID http://orcid.org/0000-0002-4210-2377

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32525028National Natural Science Foundation of China (National Science Foundation of China) 82022050, 82372662, 81972601National Natural Science Foundation of China (National Science Foundation of China) 82302967National Natural Science Foundation of China (National Science Foundation of China) 82373142Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) BE2023703Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) BK20250003
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41781708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.