ArticleNature2026
Microbiota-mediated induction of beige adipocytes in response to dietary cues.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Trial
- Revisiting gut microbiota-driven ammonia metabolism: from disease burden to physiological adaptation.Gut microbes · 2026Review
- Gut microbial signatures in poultry under low-protein diets and lysine restriction: implications for precision nutrition.Veterinary and animal science · 2026Review
- ROS-responsive small-molecule self-assembled nanocarrier-integrated hydrogels for ulcerative colitis treatment.Materials today. Bio · 2026Article
- Microbiota and Methylglyoxal-Derived AGEs: Implications in Ageing and Age-Related Disease.Life (Basel, Switzerland) · 2026Review
- Alternative Receptor Signaling for the Selective and Multifaceted Regulation of Human Brown Adipocytes.International journal of molecular sciences · 2026Review
- Gut microbiota induce browning of white adipose tissue.Nature reviews. Gastroenterology & hepatology · 2026Article
- Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
- Update of
Authors and funding
33 authors.
Takeshi Tanoue *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-3639-8834
Manabu Nagayama *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-4088-2944
Ayumi J A Roochana *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Samuel Zimmerman *Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Orr AshenbergKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Tanvi JainKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Ryo IgarashiDepartment of Integrated Medicine and Biochemistry, Keio University School of Medicine, Tokyo, Japan.
Satoshi SasajimaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Kozue TakeshitaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Nicola HetheringtonRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Nobuyuki OkahashiRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Masahiro UedaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Morichika KonishiLaboratory of Microbial Chemistry, Kobe Pharmaceutical University, Kobe, Japan.ORCID http://orcid.org/0000-0002-2424-7169
Yoshiaki NakayamaLaboratory of Microbial Chemistry, Kobe Pharmaceutical University, Kobe, Japan.
Aki MinodaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Ashwin N SkellyDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1565-3376
Yasuhiko MinokoshiDivision of Endocrinology and Metabolism, National Institute for Physiological Sciences, Okazaki, Japan.ORCID http://orcid.org/0000-0002-7119-4805
Nicholas PucciDepartment of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0002-2668-6330
Daniel R MendeDepartment of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Makoto AritaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0001-9902-0463
Hironori YamamotoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Shunji WatanabeDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Kouichi MiuraDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Scott W BehieHuman Biology Microbiome Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan.
Wataru SudaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0002-2861-9724
Toshiro SatoDepartment of Integrated Medicine and Biochemistry, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-8353-8137
Koji AtarashiDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-5422-0736
Mami MatsushitaDepartment of Nutrition, School of Nursing and Nutrition, Tenshi College, Sapporo, Japan.
Shingo KajimuraDivision of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0672-5910
Damian R PlichtaInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6555-2557
Masayuki SaitoLaboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Ramnik J XavierInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. xavier@molbio.mgh.harvard.edu.ORCID http://orcid.org/0000-0002-5630-5167
Kenya HondaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan. kenya@keio.jp.ORCID http://orcid.org/0000-0001-8937-9835
Funding
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3MDeterminants of inception of inflammation in inflammatory bowel diseasesR01DK127171 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ANANTHAKRISHNAN, ASHWIN N, XAVIER, RAMNIK J · 2021 to 2025
$5.4MCardiovascular disease, metabolic syndrome, microbes and metabolites in FHSR01HL157717 · NHLBI · BROAD INSTITUTE, INC. · PI XAVIER, RAMNIK J · 2022 to 2025
$3.9MNHLBI NIH HHS R01 HL157717NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK127171
Abstract
Interactions between diet and the gut microbiota are fundamental to metabolic health, shaping energy balance and disease susceptibility
Indexed as
Adipocytes, BeigeCuesDietGastrointestinal MicrobiomeAdipose Tissue, BrownAdipose Tissue, WhiteAdultAnimalsBile Acids and SaltsFecesFemaleFibroblast Growth FactorsGerm-Free LifeHumansMaleMiceBile Acids and Saltsfibroblast growth factor 21Fibroblast Growth FactorsReceptors, Cytoplasmic and Nuclear
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.