Evidence map›Paper›PMID 41781616›Full record

ArticleNature2026

DICER cleavage fidelity is governed by 5'-end binding pockets.

Minh Khoa Ngo, Cong Truc Le, Tuan Anh Nguyen

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Minh Khoa NgoDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong, China.
Cong Truc LeDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong, China.ORCID http://orcid.org/0000-0002-8261-2718
Tuan Anh NguyenDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong, China. tuananh@ust.hk.ORCID http://orcid.org/0000-0001-7793-2699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) depends on DICER, an essential enzyme that processes RNA precursors into small regulatory RNAs. DICER cleaves RNA precursors according to the 5'-end counting rule, in which RNA length is measured from the 5'-end

Indexed as

Ribonuclease IIIRNA CleavageAnimalsBinding SitesCryoelectron MicroscopyHumansModels, MolecularNucleic Acid ConformationNucleotide MotifsRNA, Double-StrandedRNA PrecursorsSubstrate SpecificityRibonuclease IIIRNA, Double-StrandedRNA Precursors

Identifiers

PMID41781616
PMCPMC13171623

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.