ArticleScientific reports2026
Perioperative treatments and endophthalmitis after cataract surgery in France: the national population-based ICCARE study.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cataracts surgeries are the most common ophthalmic procedure worldwide. Despite established guidelines, perioperative topical treatment practices remain heterogeneous. Clarifying real-world prescribing patterns and their association with post-operative endophthalmitis (POE) is essential to optimize postoperative care and patient safety. The aim of this study was to describe perioperative topical treatments, estimate the POE incidence, and identify associated risk factors in France. We conducted a retrospective, population-based cohort study using real-world data from the Système National des Données de Santé (SNDS), the French national health Insurance database. The study included all subjects aged 40 years or older who underwent cataract surgery in France between January 1 and December 31, 2019. The primary outcome was the 42-day postoperative incidence of POE, identified by two ICD-10 diagnostic codes. Secondary outcomes included patterns of perioperative topical drug use and risk factors associated with POE. Associated risk factors were identified using logistic regression. This study included 543,530 patients (815,621 procedures) with a mean age of 73.3 ± 9.0 years, 57.6% of women. Most patients (98.8%) had at least one topical treatment: 97.8% treated with topical antibiotics, 97.0% with steroidal anti-inflammatory eye drops, 90.6% with non-steroidal anti-inflammatory eye drops. The incidence of POE was estimated at 6.4/10,000 patients (n = 347). Male sex and a higher Charlson comorbidity index and cataract surgery in a healthcare facility with < 90% of intraoperative intracameral antibiotics were associated with an increased risk of POE, and topical antibiotics provided no additional benefit. This study conducted in France highlights that cataract surgery is commonly associated with a perioperative treatment involving three different types of eye drops. Although topical antibiotics were commonly administered (97.8%), we found no statistically significant additional benefit beyond intracameral antibiotic prophylaxis in preventing POE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.