Evidence map›Paper›PMID 41781406›Full record

ReviewNPJ science of food2026

Lycium L. flavonoids: extraction, purification, signal transduction pathways, and interactions with intestinal microbiota.

Tian Lan, Kexin Zhou, Guozhen Duan, Yuxin Zhang, Yonggui Ma, Guanghui Fan, Youchao Qi

Abstract readReview
In one paragraph

Review in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tian Lan *College of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Kexin Zhou *College of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Guozhen DuanCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Yuxin ZhangCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Yonggui MaKey Laboratory of Medicinal Animal and Plant Resources of Qinghai Tibetan Plateau, Qinghai Normal University, Xining, China.
Guanghui FanCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Youchao QiCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China. 2020990013@qhu.edu.cn.

Funding

A Major Science and Technology Project under the Qinghai Province Science and Technology Plan 2023-NK-A4
6 · The paper itself

Abstract

Flavonoids are major bioactive constituents of Lycium L. with diverse pharmacological activities. This review summarizes recent advances in the extraction, characterization, and biological functions of Lycium flavonoids (LyFs). Evidence indicates that LyFs exert antioxidant, anti-inflammatory, and immunomodulatory effects via pathways such as NF-κB and Keap1-Nrf2/ARE. Notably, LyFs act as functional prebiotics by modulating gut microbiota and short-chain fatty acid production, supporting intestinal and metabolic health.

Identifiers

PMID41781406
PMCPMC13076785

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.