Evidence map›Paper›PMID 41781040›Full record

SynthesisBMJ open2026

Understanding influences of care-seeking behaviours for diarrhoeal illnesses: a qualitative meta-synthesis.

Marissa H Miller, Skye M Hilbert, Erica N Rosser, Laura Sinko, Elizabeth C Lee, Kirsten E Wiens

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Marissa H MillerDepartment of Epidemiology and Biostatistics, Temple University Barnett College of Public Health, Philadelphia, Pennsylvania, USA.
Skye M HilbertDepartment of Epidemiology and Biostatistics, Temple University Barnett College of Public Health, Philadelphia, Pennsylvania, USA.
Erica N RosserInternational Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Laura SinkoDepartment of Nursing, Temple University Barnett College of Public Health, Philadelphia, Pennsylvania, USA.
Elizabeth C LeeDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Kirsten E WiensDepartment of Epidemiology and Biostatistics, Temple University Barnett College of Public Health, Philadelphia, Pennsylvania, USA kirsten.wiens@temple.edu.ORCID http://orcid.org/0000-0003-4093-4054

Funding

The role of unobserved cholera: implications for prevention and controlK22AI168389 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI WIENS, KIRSTEN E · 2023 to 2024
$270k
NIAID NIH HHS K22 AI168389
6 · The paper itself

Abstract

objectivesDiarrhoeal illnesses remain a leading cause of morbidity and mortality worldwide. Understanding when and where individuals seek healthcare is essential for accurately assessing disease burden and improving access to appropriate care. We conducted a meta-synthesis of qualitative research examining barriers and facilitators to care-seeking for diarrhoeal illness among individuals and caregivers of children.

designWe systematically reviewed qualitative studies examining the motivations for seeking care for diarrhoeal illness and conducted a thematic analysis to synthesise findings across studies. DATA SOURCES: PubMed, Embase, Web of Science and Global Index Medicus were searched through 3 September 2024. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: We included qualitative studies that used interviews and/or focus group discussions to examine care-seeking decisions for diarrhoeal illness. DATA EXTRACTION AND SYNTHESIS: Two independent reviewers assessed studies for eligibility, extracted study information and coded factors influencing care-seeking decisions. The two researchers then independently created thematic trees based on patterns in the coded data and, through discussion with the full research team, synthesised findings into a thematic framework.

resultsIn total, 47 studies met our inclusion criteria, 36 of which focused on caregiver decision-making for children with diarrhoea in low- and middle-income countries. Our meta-synthesis identified several key factors that influenced whether and when individuals sought care. Sociocultural norms, including locally held beliefs about disease causation, were frequently cited as influencing decisions to seek or delay formal care. Additional barriers included long travel distances to health facilities, transportation costs, limited trust in healthcare providers, negative feelings and inconsistent availability of care. Conversely, episodes perceived as severe were more likely to prompt care-seeking outside the home.

conclusionsThese findings highlight the importance of contextually grounded interventions that improve physical and financial access to care, foster trust in healthcare providers through consistent and effective service delivery and strengthen community engagement around recognising signs of severe illness and the potential benefits of timely treatment. They also underscore the need for future studies to define diarrhoea in locally relevant terms and to clearly define sources of care-seeking, as variation in these definitions can limit our full understanding of who is affected and how individuals respond to illness.

Indexed as

DiarrheaPatient Acceptance of Health CareCaregiversChildDecision MakingHealth Services AccessibilityHumansQualitative ResearchHealth ServicesINFECTIOUS DISEASESPublic healthQUALITATIVE RESEARCHSystematic Review

Identifiers

PMID41781040
PMCPMC12970062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.