Evidence map›Paper›PMID 41781036›Full record

SynthesisBMJ health & care informatics2026

Effects of a bidirectional interoperability between electronic health records and smart infusion pumps in hospital settings: a systematic review.

Sini Kuitunen, Bruna L Alves, Hanna Peitsoma, Muhammad Z Saleem, Lotta Schepel, Anna-Riia Holmström

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ health & care informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sini KuitunenClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland sini.kuitunen@helsinki.fi.ORCID http://orcid.org/0000-0002-0170-892X
Bruna L AlvesClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Hanna PeitsomaClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Muhammad Z SaleemClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Lotta SchepelClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Anna-Riia HolmströmClinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the effects of bidirectional interoperability between electronic health records (EHR) and smart infusion pumps on medication errors (MEs), system compliance and workflow efficiency and economic aspects.

methodsThis systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 criteria. The literature search on Scopus, MEDLINE (Ovid), Web of Science, Cumulated Index in Nursing and Allied Health Literature, and Evidence-Based Medicine Reviews was conducted on 3 October 2024. Peer-reviewed studies considering bidirectional interoperability between EHR and smart pumps in hospitals were included. Study selection according to a predetermined Population, Intervention, Comparison(s) and Outcome tool, data extraction and evidence quality assessment (Joanna Briggs Institute critical appraisal tool assessment and the Grading of Recommendations Assessment, Development and Evaluation approach) were carried out by two individual reviewers.

resultsSeven studies from the USA, published between 2011 and 2024, were included. The studies used variable designs to compare the effects of bidirectional interoperability between smart infusion pumps and EHR on system compliance and workflow efficiency (n=6 studies), MEs (n=3) and economic outcomes (n=2) before and after implementation. The observed effects were mainly positive; however, evidence quality was low because of the observational nature of studies. DISCUSSION: The interoperability between EHR systems and smart infusion pumps remains a relatively novel research topic. Evidence is geographically concentrated, limiting its generalisability to different healthcare systems, regulatory environments and technology adoption patterns.

conclusionWhile bidirectional interoperability may reduce MEs, improve system compliance and workflow efficiency and enhance hospitals' charging accuracy of provided care, future studies should prioritise controlled designs, robust data and economic outcomes to justify the investment. PROSPERO REGISTRATION NUMBER: CRD42024538518.

Indexed as

Electronic Health RecordsHealth Information InteroperabilityInfusion PumpsMedication ErrorsDigital HealthHospitalsHumansWorkflowelectronic health recordshealth information interoperability

Identifiers

PMID41781036
PMCPMC12970065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.