Evidence map›Paper›PMID 41779843›Full record

ArticleScience advances2026

Persistent antigen is essential for sustaining

Zhirong Mou, Roma Zayats, Enitan Salako, Nnamdi Ikeogu, Somtochukwu S Onwah, Dong Liu, Hiroshi Hamana, Hiroyuki Kishi, Da Tan, Carson Leung and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhirong MouDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0009-0002-0799-1137
Roma ZayatsDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-1934-1337
Enitan SalakoDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-3032-4335
Nnamdi IkeoguDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Somtochukwu S OnwahDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0001-7880-7961
Dong LiuCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, USA.ORCID 0000-0002-1836-2267
Hiroshi HamanaDepartment of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.ORCID 0000-0002-6964-1020
Hiroyuki KishiDepartment of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.ORCID 0000-0002-8740-5371
Da TanDepartment of Computer Science, Faculty of Science, University of Manitoba, Winnipeg, Canada.ORCID 0009-0000-7861-6786
Carson LeungDepartment of Computer Science, Faculty of Science, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-7541-9127
Janilyn ArsenioDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0003-0220-0076
Thomas T MurookaDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-3030-2726
Jude E UzonnaDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID 0000-0003-2759-0664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory CD4

Indexed as

Antigens, ProtozoanCD4-Positive T-LymphocytesImmunologic MemoryLeishmania majorLeishmaniasis, CutaneousMemory T CellsAnimalsMiceMice, TransgenicAntigens, Protozoan

Identifiers

PMID41779843
PMCPMC12959414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.