Trial reportPloS one2026
Effect of home-based isometric handgrip exercise with a commercially available device on blood pressure in older adults with hypertension: A randomized controlled trial.
Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIsometric handgrip exercise may help reduce blood pressure, but its effectiveness using inexpensive, home-based devices remains unclear. This study aimed to evaluate the impact of home-based isometric handgrip exercise on resting systolic blood pressure (SBP) in hypertensive older adults. Secondary outcomes included diastolic blood pressure (DBP), heart rate (HR), grip strength, safety, and satisfaction.
methodsA randomized controlled trial was conducted at the Comprehensive Geriatric Clinic, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. Thirty hypertensive participants aged over 60 with handgrip maximum voluntary contraction (MVC) of 10-40 kg were randomized into two groups. The intervention group (n = 15) performed isometric handgrip exercises using spring devices at 20-50% MVC. The control group (n = 15) performed non-resistive handgrip exercises. Both groups exercised 3 times/week for 8 weeks (4 sets of 2-minute holds, 1-minute rest between sets).
resultsThe intervention group showed significant reductions in SBP (-7.33 ± 9.63 mmHg, P = 0.011) and DBP (-3.6 ± 5.79 mmHg, P = 0.03). Grip strength improved in both groups, but only SBP reduction showed a significant between-group difference (-8.19 mmHg, P = 0.03). No complications were reported, and satisfaction was high in the intervention group.
conclusionHome-based isometric handgrip exercise using commercial spring devices at 20-50% MVC significantly reduced SBP in hypertensive older adults. It is a simple, safe, and affordable exercise option, suitable for those unable to perform standard aerobic activities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.