Evidence map›Paper›PMID 41779517›Full record

ArticleArquivos brasileiros de cardiologia2025

Geographic Variation in Door-to-Needle Time among Patients with STEMI from the Metropolitan Region of Rio de Janeiro: Results of the EQUITY-MI Cohort.

Eric Costa de Almeida, Felipe Neves Albuquerque, Esmeralci Ferreira, Roberto Pozzan, Pedro Pimenta de Mello Spineti, Pâmela Sousa Monteiro, Williana Oliveira de Araújo, Rhayana Vitória da Rosa Silva, Carla Maciel Caminhas, Thales Cardoso Whately and 2 more

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Article in Arquivos brasileiros de cardiologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Eric Costa de AlmeidaHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.ORCID 0009-0002-5311-3036
Felipe Neves AlbuquerqueUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.ORCID 0000-0001-8692-1115
Esmeralci FerreiraUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.ORCID 0000-0003-3230-7683
Roberto PozzanUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.
Pedro Pimenta de Mello SpinetiHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.ORCID 0000-0001-9891-676X
Pâmela Sousa MonteiroHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.
Williana Oliveira de AraújoHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.
Rhayana Vitória da Rosa SilvaHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.
Carla Maciel CaminhasUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.
Thales Cardoso WhatelyHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.
João Gabriel Monteiro JunqueiraHospital Universitário Pedro Ernesto, Rio de Janeiro, RJ - Brasil.
Denilson Campos de AlbuquerqueUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.ORCID 0000-0003-1883-6546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a gap in information regarding the reperfusion strategies used and the evolution of patients with ST-segment elevation myocardial infarction (STEMI) in the state of Rio de Janeiro.

objectiveTo assess thrombolysis time in the diverse regions of the state capital and metropolitan area of Rio de Janeiro, as well as the outcome of post-infarction heart failure.

methodsEQUITY-MI is a prospective cohort study of patients diagnosed with STEMI and referred to a single reperfusion center. Continuous variables were analyzed using the Kruskal-Wallis test, and categorical variables were analyzed using the chi-square test. In order to estimate the effect of door-to-needle time (DNT), generalized linear regression models with gamma distribution and log link function were applied, in addition to quantile regression to estimate the effect at the 25%, 50%, and 75% quantiles, both adjusted for sex, age, race, and education level. The significance level applied was 0.05.

resultsThe study included 457 patients, with a mean age of 60.4 years, 79% of whom received thrombolysis, with a median DNT of 77 minutes, and 20.9% were thrombolyzed within 30 minutes, with no statistical difference between regions (p = 0.23). The Baixada Fluminense region presented the highest adjusted mean DNT (165.9 minutes), with a time difference compared to the North Zone (0.61; 0.44 to 0.87; p = 0.003) and West Zone (0.69; 0.51 to 0.96; p = 0.022). It also presented the highest DNT in all intervals (Q25, Q50, Q75). After infarction, 63.5% of patients presented heart failure.

conclusionThere was a general delay in DNT for patients included in the EQUITY-MI study, with worse systematic performance in the Baixada Fluminense region, in addition to a high incidence of post-infarction heart failure.

Indexed as

ST Elevation Myocardial InfarctionThrombolytic TherapyTime-to-TreatmentAgedBrazilFemaleHeart FailureHumansMaleMiddle AgedProspective StudiesStatistics, NonparametricTime FactorsTreatment DelayTreatment Outcome

Identifiers

PMID41779517
PMCPMC12978378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.