Evidence map›Paper›PMID 41779510›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2026

Trypanosoma cruzi infection status in birthing individuals in three endemic provinces of Argentina: a descriptive cross-sectional study.

María Ayelen Toscani, Emmaria Danesi, Karen Klein, Luz Gibbons, Candela Belén Stella, Pablo Elías Gulayin, Mabel Berrueta, Eric Dumonteil, Claudia Herrera, Pierre Buekens and 2 more

Abstract read
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

María Ayelen ToscaniInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-7084-0660
Emmaria DanesiInstituto Nacional de Parasitología "Dr. Mario Fatala Chabén" (INP), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-2413-0240
Karen KleinInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-4619-5432
Luz GibbonsInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-0235-1635
Candela Belén StellaInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0009-0001-8056-1531
Pablo Elías GulayinInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-4709-7543
Mabel BerruetaInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-7915-5643
Eric DumonteilTulane University, Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, USA.ORCID http://orcid.org/0000-0001-9376-0209
Claudia HerreraTulane University, Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, USA.ORCID http://orcid.org/0000-0002-9009-4201
Pierre BuekensTulane University, Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, USA.ORCID http://orcid.org/0000-0002-4294-8559
María Luisa CafferataInstituto de Efectividad Clínica y Sanitaria (IECS), Ciudad Autónoma de Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-9928-5522
BETTY Collaborative Group

Funding

Development of Improved Serological Diagnostic and Parasite Genotyping Tools for Congenital Chagas DiseaseR01HD094955 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI Claudia P Herrera · 2019 to 2026
$3.2M
NICHD NIH HHS R01 HD094955
6 · The paper itself

Abstract

backgroundChagas disease remains a public health challenge with underexplored prevalence and diagnosis in endemic areas. We assessed Trypanosoma cruzi infection screening among birthing individuals in three endemic provinces in northern Argentina.

methodsT. cruzi-seropositive birthing individuals with at least one positive or indeterminate test were enrolled during the postpartum period to confirm seropositivity by indirect hemagglutination (IHA) and enzyme-linked immunosorbent (ELISA) assays.

resultsAmong 40,035 deliveries, the T. cruzi infection rate was 1.9%. Confirmatory serology revealed 77.6% positivity, 9.3% negativity, and 13.0% discordance.

conclusionsThese findings highlight the need for confirmatory testing and improved diagnostic strategies in endemic regions.

Indexed as

Antibodies, ProtozoanChagas DiseaseEndemic DiseasesTrypanosoma cruziAdultArgentinaCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHemagglutination TestsHumansPregnancyPrevalenceSeroepidemiologic StudiesYoung AdultAntibodies, Protozoan

Identifiers

PMID41779510
PMCPMC12990784

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.