Evidence map›Paper›PMID 41779508›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2026

Pure neural leprosy in a child: case report and diagnostic challenges.

Hortência Aparecida Dos Reis Santana, Isabela Pedra Diamantino, Jean Carlos de Araújo Arruda, Pedro Alysson Mota da Silva, Gabrieli Souza Dos Santos, Jonatas César Matos de Oliveira, Vanessa Oliveira de Souza, Clécio Ribeiro Costa, Andrea Pereira Macke, Karen Nepomuceno Sá Teles and 3 more

Abstract readCase Reports
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hortência Aparecida Dos Reis SantanaUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0008-7302-6654
Isabela Pedra DiamantinoUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0006-0563-0441
Jean Carlos de Araújo ArrudaUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0009-5556-7964
Pedro Alysson Mota da SilvaUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0009-9981-607X
Gabrieli Souza Dos SantosUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0000-0070-804X
Jonatas César Matos de OliveiraUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0008-0501-714X
Vanessa Oliveira de SouzaUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0004-4453-7464
Clécio Ribeiro CostaCentro de Saúde Leonídia Ayres de Almeida, Programa de Controle da Hanseníese, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0004-2600-5202
Andrea Pereira MackeCentro de Saúde Leonídia Ayres de Almeida, Programa de Controle da Hanseníese, Barreiras, BA, Brasil.ORCID http://orcid.org/0009-0006-5900-4040
Karen Nepomuceno Sá TelesCentro de Saúde Leonídia Ayres de Almeida, Programa de Controle da Hanseníese, Barreiras, BA, Brasil.ORCID http://orcid.org/0000-0001-6699-8027
Fernando do Prado VieiraUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0000-0003-2951-6556
Filipe Rocha LimaUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Hospital das Clínicas, Divisão de Dermatologia, Departamento de Clínica Médica, Ribeirão Preto, SP, Brasil.ORCID http://orcid.org/0000-0001-7629-4963
Jonilson Berlink LimaUniversidade Federal do Oeste da Bahia, Centro das Ciências Biológicas e da Saúde, Barreiras, BA, Brasil.ORCID http://orcid.org/0000-0002-1403-4768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pure neural leprosy (PNL) is infrequent and manifests exclusively in the peripheral nerves without skin involvement, making the diagnosis more complex. We report the case of a 10-year-old child with muscle atrophy and sensory loss, diagnosed through clinical evaluation, grade 2 disability, and a positive anti-PGL-I test. The slit-skin smear (SSS) was negative for acid-fast bacilli. After 12 months of multidrug therapy, esthesiometric sensitivity improved; however, neurological deficits persisted, requiring anti-inflammatory treatment and physiotherapy. This case highlights the importance of early diagnosis and treatment for preventing disabilities. Tools, such as anti-PGL-I tests and imaging, are crucial, particularly in resource-limited settings.

Indexed as

Leprosy, TuberculoidChildHumansMale

Identifiers

PMID41779508
PMCPMC12990783

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.