SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026
Prevalence of developmental defects of enamel in Brazil: a systematic review and meta-analysis.
Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo estimate the pooled prevalence of developmental defects of enamel (DDE), specifically molar-incisor hypomineralisation (MIH), hypomineralised second primary molars (HSPM), enamel hypoplasia, and dental fluorosis, in the Brazilian population.
methodsA comprehensive literature search was performed through PubMed, Web of Science, Scopus, Embase, SciELO and LILACS databases following PRISMA guidelines. The grey literature search was conducted on Google Scholar. Cross-sectional studies reporting prevalence data of DDE in Brazil were included. Risk of bias was assessed using the Joanna Briggs Institute Checklist for Prevalence Studies. A random-effects meta-analysis was performed to determine the pooled prevalence. Subgroup analyses were performed to investigate potential sources of heterogeneity.
resultsFifty-eight studies were included in the quantitative synthesis, comprising 42,337 participants across all five Brazilian geographic regions. The pooled prevalence was 15.6% (95% CI: 13.2%-18.4%; I
conclusionDDEs are highly prevalent in Brazil, with geographic region and dentition type contributing to variability.
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