Evidence map›Paper›PMID 41779194›Full record

ArticleClinical neuroradiology2026

Mid- and Long-Term Outcomes Following Flow Diversion for Carotid-Ophthalmic Aneurysms: a Single-Centre Experience.

Gian Marco Frigerio, Sara Sciacca, Jeremy Lynch, Sahan Guruge, Matthew Benger, Parthiban Balasundaram, Thomas Booth, Naga Kandasamy

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Article in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Gian Marco FrigerioDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Sara SciaccaDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Jeremy LynchDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Sahan GurugeDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Matthew BengerDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Parthiban BalasundaramDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Thomas BoothDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Naga KandasamyDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, United Kingdom. naga.kandasamy@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFlow diverter stents (FDS) have shown promise in treating carotid-ophthalmic aneurysms (COAs), but mid- to long-term data remain limited. This study reports our institutional experience using FDS for unruptured COAs.

methodsBetween August 2010 and September 2023, 105 unruptured COAs in 99 patients (87 females, mean age 54 ± 14 years) were retrospectively analyzed. The anatomical relationship between the ophthalmic artery (OphA) and the aneurysm was classified as Type 1 (separate), Type 2 (neck), or Type 3 (dome). Patients were treated with FDS alone or with adjunctive coiling. Clinical and angiographic outcomes, including visual complications, were assessed.

resultsTechnical success was 98.1%. At a mean follow-up of 38.5 months, complete occlusion was achieved in 89.1% and adequate occlusion in 98.0%. Occlusion rates were comparable across types, with a trend toward lower rates in Type 2. Retreatment was required in 1.0%. Major adverse events occurred in 1.0%, neurological complications in 3.0%, and in-stent stenosis in 2.0%. New visual deficits occurred in 6.1% (4.0% transient, 2.0% permanent). Aneurysm size > 12 mm was significantly associated with persistent symptoms (p = 0.003). Preoperative visual symptoms were the only independent predictor of poor visual outcome. Outcomes were comparable between FDS-only and FDS+coiling groups.

conclusionFDS, with or without coiling, is a safe and effective treatment for COAs, achieving durable occlusion and generally favorable visual outcomes. The OphA-aneurysm relationship may influence occlusion, although residual filling may also reflect physiological flow preservation. Early treatment is essential in patients with large aneurysms and visual symptoms.

Indexed as

Carotid Artery DiseasesEndovascular ProceduresIntracranial AneurysmOphthalmic ArteryStentsAdultAgedCerebral AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeBrain aneurysmEndovascular treatmentFlow diversionFlow diversion outcomeInternal carotid arteryIntracranial aneurysmLow morbidity endovascularLow recurrence ratesLow retreatment ratesPara-ophthalmicParaophthalmicRobust treatment endovascularSafe flow diversion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.