Evidence map›Paper›PMID 41778905›Full record

Trial reportExperimental physiology2026

Ultrasound predicts skeletal muscle fat infiltration in healthy middle-aged and young adults: Validation against MRI.

R K Holsgrove-West, P M Słowiński, E Svensen, C Koscien, J Fulford, R Revuelta Iniesta, B T Wall, F B Stephens

Abstract readRandomized Controlled TrialValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R K Holsgrove-WestPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0003-3696-0575
P M SłowińskiDepartment of Mathematics and Statistics, Faculty of Environment, Science and Economy, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0002-6612-9902
E SvensenPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.
C KoscienPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.
J FulfordMedical Imaging Department, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
R Revuelta IniestaPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.
B T WallPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0002-6019-6709
F B StephensPublic Health and Sport Sciences, Medical School, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0001-6312-5351

Funding

EPSRC Healthcare Technologies EP/T518049/1Welcome Trust Translational Research
6 · The paper itself

Abstract

This study developed an ultrasound prediction equation for measuring fat fraction in lower limb muscles of healthy middle-aged and young participants and applied it in a randomised controlled trial (RCT) to assess the relationship between fat fraction and strength in exercising and non-exercising females. Twenty-eight participants were recruited into <40 years (10m, 5f, age 28.9 ± 5.3 years, body mass index (BMI) 23.6 ± 2.3 kg m

Indexed as

Adipose TissueMuscle, SkeletalAdultExerciseFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMuscle StrengthUltrasonographyYoung Adultageingechointensityfat infiltrationmagnetic resonance imagingmuscleultrasound

Identifiers

PMID41778905
PMCPMC13140627

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.