Evidence map›Paper›PMID 41778712›Full record

ArticleNeural regeneration research2026

Modulation of the regenerative microenvironment within acellular nerve allografts using tacrolimus improves nerve regeneration.

Jesús A Acevedo Cintrón, Jonathon Blake Schofield, Daniel A Hunter, Pranay Singh, Alexa M Negrón Morales, Lauren Schellhardt, Susan E Mackinnon, Matthew D Wood

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesús A Acevedo CintrónDivision of Plastic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Jonathon Blake Schofield
Daniel A Hunter
Pranay Singh
Alexa M Negrón Morales
Lauren Schellhardt
Susan E Mackinnon
Matthew D WoodORCID 0000-0001-8132-6827

Funding

Neuroscience Training Program at Washington UniversityT32NS121881 · NINDS · WASHINGTON UNIVERSITY · PI Martha W Bagnall, Daniel Kerschensteiner · 2021 to 2026
$3.1M
T cell roles in regeneration across nerve graft alternativesR01NS115960 · NINDS · WASHINGTON UNIVERSITY · PI WOOD, MATTHEW D. · 2020 to 2024
$1.8M
The role of the inflammatory microenvironment in Acellular Nerve Allografts (ANAs) repairing nerve gapsF31NS130990 · NINDS · WASHINGTON UNIVERSITY · PI ACEVEDO CINTRÓN, JESÚS ALBERTO · 2023 to 2025
$111k
NINDS NIH HHS F31 NS130990NINDS NIH HHS R01 NS115960NINDS NIH HHS T32 NS121881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acellular nerve allograftimmunosuppressionmacrophagesmicroenvironmentnerve gaposteopontin (SPP1)peripheral nerve regenerationSchwann cellstacrolimus (FK506)transcriptome analysis

Identifiers

PMID41778712
PMCPMC13568610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.