Evidence map›Paper›PMID 41778551›Full record

ArticleJournal of the American Heart Association2026

Machine Learning-Enhanced TCAB Score for Predicting Postoperative Ischemic Stroke After CABG.

Yingjian Pei, Guitao Zhang, Wenbo Li, Yao Feng, Nan Li, Na Zhao, Yajun Ma, Xinmin Liu, Qilin Zhou, Fei Xu and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yingjian PeiDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0009-0008-0648-0013
Guitao ZhangDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0003-0337-705X
Wenbo LiDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Yao FengDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0001-7923-8158
Nan LiDepartment of Neurology WuAn First People's Hospital Handan Hebei Province China.
Na ZhaoDepartment of Radiology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Yajun MaDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Xinmin LiuDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0001-5497-8491
Qilin ZhouDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0003-4418-9290
Fei XuDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0003-4211-6338
Yinghua ZhouDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0009-0000-7215-3987
Shujuan LiDepartment of Neurology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0003-4740-9615

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative acute ischemic stroke remains a critical complication of coronary artery bypass grafting. This study aimed to develop a novel Total Cerebral Atherosclerosis Burden (TCAB) score for predicting the risk of AIS post-coronary artery bypass grafting.

methodsA prospective cohort of patients undergoing coronary artery bypass grafting was enrolled. The TCAB score was calculated by summing stenosis severity grades (0: <50%, 1: 50-69%, 2: 70-99%, 3: 100%) across all intracranial and extracranial artery segments. Primary outcome was in-hospital ischemic stroke. Multivariable logistic regression models adjusted for key clinical covariates were used to evaluate the association between TCAB and clinical outcomes.

resultsAmong 909 included patients, the mean TCAB score was significantly higher in patients with in-hospital ischemic stroke compared with those without (8 versus 2,

conclusionsThe TCAB score, enhanced by machine learning, effectively predicted in-hospital ischemic stroke, 1-year ischemic stroke, and 1-year major adverse cardiovascular and cerebrovascular events post-coronary artery bypass grafting. It offers a practical tool for guiding preoperative revascularization and intraoperative embolic protection.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseIntracranial ArteriosclerosisIschemic StrokeMachine LearningPostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedPredictive Learning ModelsPredictive Value of TestsProspective StudiesRisk AssessmentRisk Factorsacute ischemic strokeatherosclerotic burdencoronary artery bypass graftingmachine learningrisk stratification

Identifiers

PMID41778551
PMCPMC13055656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.