Evidence map›Paper›PMID 41778299›Full record

ArticleClinical advances in periodontics2026

Flap perfusion of superficial split flap design for guided bone regeneration: A case report with ultrasonography.

Oscar Durán-Garnica, Karen Villarreal-Arizpe, Amanda Rodríguez, Oliver Kripfgans, Hsun-Liang Chan

Abstract readCase Reports
In one paragraph

Article in Clinical advances in periodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Oscar Durán-GarnicaDivision of Periodontology, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID https://orcid.org/0009-0009-9500-1391
Karen Villarreal-ArizpeDivision of Periodontology, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-7023-8274
Amanda RodríguezDepartment of Periodontology, University of Illinois Chicago College of Dentistry, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-6011-6708
Oliver KripfgansDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-2905-1496
Hsun-Liang ChanDivision of Periodontology, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-5952-0447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEffective flap management is crucial for successful bone regeneration procedures. Traditional flap release has been performed by the deep split design; recently, the superficial split design revives for its proposed anatomical and biomechanical advantages. To understand the risk of this new flap management design on flap vitality, the aim of this case report is to investigate the perfusion of the flap with ultrasound.

methodsA single patient with an edentulous ridge exhibiting a horizontal bone deficiency underwent a regenerative procedure utilizing the superficial split technique (Secured Anatomy-Driven Flap Extension [SAFE] technique). Ultrasonography assessments were conducted before the surgery (baseline [BL]) and at days (D) 3, 10, 21, and at 5 months (MO) post-surgery. They included brightness-mode and color velocity/power (CV/CP) at the buccal flap. CV and CP cine loops (videos) were recorded to assess tissue perfusion by surrogate. Three distinct regions of interest were selected, i.e., keratinized mucosa (KM), lining mucosa (LM), and muscle (M).

resultsKM perfusion (CV) increased significantly at D3, then decreased at D10 and D21. The 5MO value was insignificant from BL. LM perfusion non-significantly decreased at D3 and D10, and returned to BL at D21 and 5MO. Muscle perfusion showed a nonsignificant decreasing trend. CP showed nonsignificant changes post-surgery relative to BL for the three regions.

conclusionUltrasound could be able to longitudinally quantify post-surgery tissue perfusion with sufficient spatial resolution to assess KM, LM, and M separately. This pilot ultrasonography study may ease the concern that the superficial split flap design jeopardizes flap vitality. KEY POINTS: Preliminary ultrasound data suggested that the Secured Anatomy-Driven Flap Extension (SAFE) technique, based on the superficial split approach, does not jeopardize flap vitality. Ultrasound may be a valuable tool for monitoring oral wound healing and guiding treatment decisions. PLAIN LANGUAGE SUMMARY: Ultrasound imaging technology, being a superior modality for evaluating soft tissue characteristics and able to quantify blood perfusion, is becoming a promising research tool to study oral wound healing. This case report used dental ultrasound to monitor the blood flow of an oral wound for 5 months after a jawbone augmentation procedure. Ultrasound showed gum blood flow peaked at day 3 after the surgery and decreased exponentially until 5 months. Mucosa and muscle may have various blood perfusion recovery patterns than gum tissues that deserve further investigation.

Indexed as

Bone RegenerationGuided Tissue Regeneration, PeriodontalSurgical FlapsHumansUltrasonographyflap designjawbonemicrosurgeryridge augmentationultrasonographywound healing

Identifiers

PMID41778299
PMCPMC13603055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.